Type IV pili: dynamics, biophysics and functional consequences

L Craig, KT Forest, B Maier - Nature reviews microbiology, 2019 - nature.com
The surfaces of many bacteria are decorated with long, exquisitely thin appendages called
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …

Bacterial adhesion at the single-cell level

C Berne, CK Ellison, A Ducret, YV Brun - Nature Reviews Microbiology, 2018 - nature.com
The formation of multicellular microbial communities, called biofilms, starts from the
adhesion of a few planktonic cells to the surface. The transition from a free-living planktonic …

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Mechanomicrobiology: how bacteria sense and respond to forces

YF Dufrêne, A Persat - Nature Reviews Microbiology, 2020 - nature.com
Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

Development of antibiofilm therapeutics strategies to overcome antimicrobial drug resistance

S Nadar, T Khan, SG Patching, A Omri - Microorganisms, 2022 - mdpi.com
A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …

How bacteria recognise and respond to surface contact

TEP Kimkes, M Heinemann - FEMS microbiology reviews, 2020 - academic.oup.com
Bacterial biofilms can cause medical problems and issues in technical systems. While a
large body of knowledge exists on the phenotypes of planktonic and of sessile cells in …

A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa

BJ Laventie, M Sangermani, F Estermann, P Manfredi… - Cell host & …, 2019 - cell.com
The opportunistic human pathogen Pseudomonas aeruginosa effectively colonizes host
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …

Formation, development, and cross-species interactions in biofilms

A Luo, F Wang, D Sun, X Liu, B Xin - Frontiers in Microbiology, 2022 - frontiersin.org
Biofilms, which are essential vectors of bacterial survival, protect microbes from antibiotics
and host immune attack and are one of the leading causes that maintain drug-resistant …

AHLs-mediated quorum sensing threshold and its response towards initial adhesion of wastewater biofilms

J Wang, Q Liu, D Dong, H Hu, B Wu, H Ren - Water Research, 2021 - Elsevier
Quorum sensing (QS) plays a crucial role during initial biofilm formation, however the QS
threshold and the response of biofilm formation towards N-acyl-homoserine lactones (AHLs) …

New insight into the early stages of biofilm formation

CR Armbruster, MR Parsek - Proceedings of the National …, 2018 - National Acad Sciences
Biofilms are loosely defined as aggregates of bacteria encased in a self-produced matrix (1–
3). Many bacterial species are known to produce biofilms when they attach to surfaces. They …