Polygenic autoinflammatory diseases (AIDs), such as systemic juvenile idiopathic arthritis
(sJIA), adult-onset Still's disease, Kawasaki disease, idiopathic recurrent pericarditis (IRP) …

Introduction: The past decade has seen increasingly rapid advances in understanding the
pathogenic nature of adult-onset Still's disease (AOSD) and its shared symptoms with the …

Ferritin is an iron-binding molecule, which comprises 24 subunits, heavy (FeH) and light
(FeL) subunits, suggested to have a pathogenic role by the 'hyperferritinemic syndrome'. In …

COVID-19 is a respiratory viral illness that can have life threatening complications. While the
short-term sequela of COVID-19, including cytokine storm, is relatively well known, the long …

Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases.
There are now several agents available on the market capable of blocking IL-1. The proven …

The neural, the endocrine, and the immune systems are studied as distinct districts in
physiological and pathological settings. However, these systems must be investigated with …

Background: Systemic Juvenile Idiopathic Arthritis (SJIA)/Pediatric Still's disease is
associated with different phenotypes and outcomes from currently available treatments …

Objectives To assess drug retention rates (DRRs) and reasons for discontinuation of
biologic disease-modifying antirheumatic drugs (bDMARDs) in a large monocentric cohort of …

ABSTRACT Introduction Adult onset Still disease (AOSD) is a rare systemic inflammatory
condition. The clinical spectrum of this disease ranges from self-limiting forms with mild …

Objectives To compare the ability of the modified Systemic Manifestation Score (mSMS) and
the mPouchot score to distinguish adult-onset Still's disease (AOSD) with high disease …