Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

Background During the COVID-19 pandemic general medical complications have received
the most attention, whereas only few studies address the potential direct effect on mental …

Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

Aims The aim of this study was to investigate the causal relationship and evidence of an
association between increased adiposity and the risk of incident cardiovascular disease …

Decades of research have revealed numerous risk factors for mental disorders beyond
genetics, but their consistency and magnitude remain uncertain. We conducted a “meta …

Leading biological hypotheses propose that biological changes may underlie major
depressive disorder onset and relapse/recurrence. Here, we investigate if there is …

Background Prenatal and perinatal insults are implicated in the aetiopathogenesis of
psychotic disorders but the consistency and magnitude of their associations with psychosis …

Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

Objective: Efforts to prevent depression, the leading cause of disability worldwide, have
focused on a limited number of candidate factors. Using phenotypic and genomic data from …