The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

F Lyko - Nature Reviews Genetics, 2018 - nature.com
The DNA methyltransferase (DNMT) family comprises a conserved set of DNA-modifying
enzymes that have a central role in epigenetic gene regulation. Recent studies have shown …

[HTML][HTML] Zinc-finger proteins in health and disease

M Cassandri, A Smirnov, F Novelli, C Pitolli… - Cell death …, 2017 - nature.com
Zinc-finger proteins (ZNFs) are one of the most abundant groups of proteins and have a
wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are …

[HTML][HTML] Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

NE Reticker-Flynn, W Zhang, JA Belk, PA Basto… - Cell, 2022 - cell.com
For many solid malignancies, lymph node (LN) involvement represents a harbinger of
distant metastatic disease and, therefore, an important prognostic factor. Beyond its utility as …

Clinical and genomic characterization of treatment-emergent small-cell neuroendocrine prostate cancer: a multi-institutional prospective study

R Aggarwal, J Huang, JJ Alumkal, L Zhang… - Journal of Clinical …, 2018 - ascopubs.org
Purpose The prevalence and features of treatment-emergent small-cell neuroendocrine
prostate cancer (t-SCNC) are not well characterized in the era of modern androgen receptor …

[HTML][HTML] The translational landscape of the human heart

S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz… - Cell, 2019 - cell.com
Gene expression in human tissue has primarily been studied on the transcriptional level,
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …

[HTML][HTML] The cellosaurus, a cell-line knowledge resource

A Bairoch - Journal of biomolecular techniques: JBT, 2018 - ncbi.nlm.nih.gov
The Cellosaurus is a knowledge resource on cell lines. It aims to describe all cell lines used
in biomedical research. Its scope encompasses both vertebrates and invertebrates …

The GeneCards suite: from gene data mining to disease genome sequence analyses

G Stelzer, N Rosen, I Plaschkes… - Current protocols in …, 2016 - Wiley Online Library
GeneCards, the human gene compendium, enables researchers to effectively navigate and
inter‐relate the wide universe of human genes, diseases, variants, proteins, cells, and …

Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches

J Beermann, MT Piccoli, J Viereck… - Physiological …, 2016 - journals.physiology.org
Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …

[HTML][HTML] The molecular signatures database hallmark gene set collection

A Liberzon, C Birger, H Thorvaldsdóttir, M Ghandi… - Cell systems, 2015 - cell.com
Summary The Molecular Signatures Database (MSigDB) is one of the most widely used and
comprehensive databases of gene sets for performing gene set enrichment analysis. Since …

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

NA O'Leary, MW Wright, JR Brister, S Ciufo… - Nucleic acids …, 2016 - academic.oup.com
The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains
and curates a publicly available database of annotated genomic, transcript, and protein …