The biological function of m6A reader YTHDF2 and its role in human disease

J Wang, A Lu - Cancer cell international, 2021 - Springer
Abstract N6-methyladenosine (m6A) modification is a dynamic and reversible post-
transcriptional modification and the most prevalent internal RNA modification in eukaryotic …

Linking the YTH domain to cancer: the importance of YTH family proteins in epigenetics

R Shi, S Ying, Y Li, L Zhu, X Wang, H Jin - Cell Death & Disease, 2021 - nature.com
Abstract N6-methyladenosine (m6A), the most prevalent and reversible modification of
mRNA in mammalian cells, has recently been extensively studied in epigenetic regulation …

Main N6-methyladenosine readers: YTH family proteins in cancers

XY Dai, L Shi, Z Li, HY Yang, JF Wei, Q Ding - Frontiers in Oncology, 2021 - frontiersin.org
Among the over 150 RNA modifications, N6-methyladenosine (m6A) is the most abundant
internal modification in eukaryotic RNAs, not only in messenger RNAs, but also in …

Regulation of N6-methyladenosine (m6A) RNA methylation in microglia-mediated inflammation and ischemic stroke

F Zhang, Y Ran, M Tahir, Z Li, J Wang… - Frontiers in cellular …, 2022 - frontiersin.org
N6-methyladenosine (m6A) is the most abundant post-transcription modification, widely
occurring in eukaryotic mRNA and non-coding RNA. m6A modification is highly enriched in …

RNA m6A methylation in cancer

Z Wang, J Zhou, H Zhang, L Ge, J Li… - Molecular …, 2023 - Wiley Online Library
N 6‐methyladenosine (m6A) is one of the most abundant internal modifications in eukaryotic
messenger RNAs (mRNAs) and non‐coding RNAs (ncRNAs). It is a reversible and dynamic …

The m6A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay

D Macveigh-Fierro, A Cicerchia… - Proceedings of the …, 2022 - National Acad Sciences
The role of N6-methyladenosine (m6A) modifications has increasingly been associated with
a diverse set of roles in modulating viruses and influencing the outcomes of viral infection …

RNA N6-methyladenosine modification, spermatogenesis, and human male infertility

Z Cai, Y Niu, H Li - Molecular Human Reproduction, 2021 - academic.oup.com
Abstract RNA N6-methyladenosine (m6A) modification is one of the main forms of
posttranscriptional modification, and its dysregulation is involved in a series of pathological …

Genome-wide identification, characterization, and expression analysis of m6A readers-YTH domain-containing genes in alfalfa

S Fan, X Xu, J Chen, Y Yin, Y Zhao - BMC genomics, 2024 - Springer
Eukaryotic messenger RNAs (mRNAs) are often modified with methyl groups at the N6
position of adenosine (m6A), and these changes are interpreted by YTH domain-containing …

RNA N6-methyladenosine modifications and its roles in Alzheimer's disease

R Zhang, Y Zhang, F Guo, S Li, H Cui - Frontiers in cellular …, 2022 - frontiersin.org
The importance of epitranscriptomics in regulating gene expression has received
widespread attention. Recently, RNA methylation modifications, particularly N6 …

The m6A epitranscriptome opens a new charter in immune system logic

Z Ma, X Gao, Y Shuai, X Xing, J Ji - Epigenetics, 2021 - Taylor & Francis
ABSTRACT N6-methyladenosine (m6A), the most prevalent RNA internal modification, is
present in most eukaryotic species and prokaryotes. Studies have highlighted an intricate …