Over the recent years, much has been unraveled about the pro-inflammatory properties of
various mitochondrial molecules once they are leaving the mitochondrial compartment. On …

While originally characterized as a collection of related syndromes, cystic fibrosis (CF) is
now recognized as a single disease whose diverse symptoms stem from the wide tissue …

Significance: Mitochondria, vital cellular power plants to generate energy, are involved in
immune responses. Mitochondrial damage-associated molecular patterns (DAMPs) are …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Adenosine triphosphate (ATP) has been well established as an important extracellular
ligand of autocrine signaling, intercellular communication, and neurotransmission with …

The simplest cell-like structure, the lipid bilayer vesicle, can respond to mechanical
deformation by elastic membrane dilation/thinning and curvature changes. When a protein is …

The colonic epithelium has both absorptive and secretory functions. The transport is
characterized by a net absorption of NaCl, short-chain fatty acids (SCFA), and water …

Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway
surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B …

The ability for long-range communication through intercellular calcium waves is inherent to
cells of many tissues. A dual propagation mode for these waves includes passage of IP3 …

The responses of rabbit urinary bladder to hydrostatic pressure changes and to electrical
stimulation have been investigated using both the Ussing chamber and a superfusion …