Background: Contemporary first-line antiretrovirals have considerably reduced liability for
clinically significant drug–drug interactions (DDI). This systematic review evaluates the …

Although highly treatable with simplified medication regimens, HIV self-management
includes complex and related behaviors including retention in care, medication adherence …

Background Prevalence of potential drug–drug interactions (PDDIs) between antiretroviral
drugs (ARVs) and co-medications was high in 2008 in a Swiss HIV Cohort Study (SHCS) …

Coadministration with acid‐reducing agents (ARAs), including proton pump inhibitors (PPIs),
histamine H2‐receptor antagonists (H2 blockers), and antacids has been demonstrated to …

Background Human immunodeficiency virus (HIV) chronicity in the midst of old age
multiplies the risk for chronic non communicable diseases. The old are predisposed to drug …

Treatment of HIV in South Africa is informed by national guidelines, which are regularly
updated. Ongoing training of healthcare workers is vital for optimal patient care, but is …

Objectives: Self-medication, also known as the use of over-the-counter drugs, can be
defined as the economical choice of using treatments that have not been prescribed …

Background Antibiotic overuse is a major public health challenge worldwide and it can result
in the emergence and spread of drug resistance. In Mozambique, there are limited data …

Abstract Introduction: In December 2019, dolutegravir-based treatment was recommended
as first-line antiretroviral therapy (ART) in South Africa. Dolutegravir has clinically significant …

Background Antiretrovirals have the potential to cause drug interactions leading to inefficacy
or toxicity via induction of efflux transporters through nuclear receptors, altering drug …