Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Triclosan exposure, transformation, and human health effects

LM Weatherly, JA Gosse - Journal of Toxicology and …, 2017 - Taylor & Francis
Triclosan (TCS) is an antimicrobial used so ubiquitously that 75% of the US population is
likely exposed to this compound via consumer goods and personal care products. In …

[HTML][HTML] Povidone iodine in wound healing: A review of current concepts and practices

PL Bigliardi, SAL Alsagoff, HY El-Kafrawi… - International Journal of …, 2017 - Elsevier
Background Of the many antimicrobial agents available, iodophore-based formulations such
as povidone iodine have remained popular after decades of use for antisepsis and wound …

Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants

P Blanco, S Hernando-Amado, JA Reales-Calderon… - Microorganisms, 2016 - mdpi.com
Bacterial multidrug efflux pumps are antibiotic resistance determinants present in all
microorganisms. With few exceptions, they are chromosomally encoded and present a …

Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential

C Pal, J Bengtsson-Palme, E Kristiansson… - BMC genomics, 2015 - Springer
Background Antibacterial biocides and metals can co-select for antibiotic resistance when
bacteria harbour resistance or tolerance genes towards both types of compounds. Despite …

[HTML][HTML] A comprehensive review on current technologies for removal of endocrine disrupting chemicals from wastewaters

D Azizi, A Arif, D Blair, J Dionne, Y Filion, Y Ouarda… - Environmental …, 2022 - Elsevier
In the recent years, endocrine disrupting compounds (EDCs) has received increasing
attention due to their significant toxic effects on human beings and wildlife by affecting their …

BacMet: antibacterial biocide and metal resistance genes database

C Pal, J Bengtsson-Palme, C Rensing… - Nucleic acids …, 2014 - academic.oup.com
Antibiotic resistance has become a major human health concern due to widespread use,
misuse and overuse of antibiotics. In addition to antibiotics, antibacterial biocides and metals …

Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance

L Fernández, REW Hancock - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The substantial use of antibiotics in the clinic, combined with a dearth of new antibiotic
classes, has led to a gradual increase in the resistance of bacterial pathogens to these …

[HTML][HTML] Antibiotics in late clinical development

P Fernandes, E Martens - Biochemical pharmacology, 2017 - Elsevier
Most pharmaceutical companies have stopped or have severely limited investments to
discover and develop new antibiotics to treat the increasing prevalence of infections caused …

Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing

MMC Buckner, ML Ciusa… - FEMS microbiology …, 2018 - academic.oup.com
Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial
infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) …