The molecular basis of predicting atherosclerotic cardiovascular disease risk

M Nayor, KJ Brown, RS Vasan - Circulation research, 2021 - Am Heart Assoc
Atherosclerotic cardiovascular disease (ASCVD) proceeds through a series of stages:
initiation, progression (or regression), and complications. By integrating known biology …

Coronary computed tomography vs. cardiac magnetic resonance imaging in the evaluation of coronary artery disease

LD Weberling, D Lossnitzer, N Frey, F André - Diagnostics, 2022 - mdpi.com
Coronary artery disease (CAD) represents a widespread burden to both individual and
public health, steadily rising across the globe. The current guidelines recommend non …

Applied coronary physiology for planning and guidance of percutaneous coronary interventions. A clinical consensus statement from the European Association of …

J Escaned, C Berry, B De Bruyne, A Shabbir… - EuroIntervention, 2023 - sfera.unife.it
The clinical value of fractional flow reserve and non-hyperaemic pressure ratios are well
established in determining an indication for percutaneous coronary intervention (PCI) in …

Intraplaque myeloperoxidase activity as biomarker of unstable atheroma and adverse clinical outcomes in human atherosclerosis

J Nadel, S Tumanov, SMY Kong, W Chen, N Giannotti… - JACC: Advances, 2023 - jacc.org
Background The detection of unstable atherosclerosis remains elusive. Intraplaque
myeloperoxidase (MPO) activity causes plaque destabilization in preclinical models, holding …

Age-and sex-specific nomographic CT quantitative plaque data from a large international cohort

G Tzimas, GS Gulsin, RJ Everett, M Akodad… - Cardiovascular …, 2024 - jacc.org
Background With growing adoption of coronary computed tomographic angiography (CTA),
there is increasing evidence for and interest in the prognostic importance of atherosclerotic …

Reduction of myocardial infarction and all-cause mortality associated to statins in patients without obstructive CAD

KA Øvrehus, A Diederichsen, EL Grove… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this work was to evaluate the prognostic impact of statin therapy in
symptomatic patients without obstructive CAD. Background Information on the prognostic …

The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do

P Wang, H Qiao, RJ Wang, R Hou, J Guo - BMC Cardiovascular Disorders, 2020 - Springer
Background Percutaneous coronary intervention (PCI) is a common treatment for patients
with coronary heart disease, and intra-stent restenosis (ISR) is a serious complication after …

SIRM–SIC appropriateness criteria for the use of Cardiac Computed Tomography. Part 1: Congenital heart diseases, primary prevention, risk assessment before …

A Esposito, M Francone, D Andreini, V Buffa… - La radiologia …, 2021 - Springer
In the past 20 years, Cardiac Computed Tomography (CCT) has become a pivotal technique
for the noninvasive diagnostic work-up of coronary and cardiac diseases. Continuous …

The atherosclerosis profile by coronary computed tomography angiography (CTA) in symptomatic patients with coronary artery calcium score zero

G Feuchtner, C Beyer, F Barbieri, P Spitaler, W Dichtl… - Diagnostics, 2022 - mdpi.com
(1) Background: Whether it is safe to exclude coronary artery disease (CAD) in symptomatic
patients with coronary artery calcium score (CACS 0), is an open debate. To compare …

Endothelial shear stress computed from coronary computed tomography angiography: A direct comparison to intravascular ultrasound

D Hakim, AU Coskun, C Maynard, Z Pu… - Journal of …, 2023 - Elsevier
Introduction Intravascular ultrasound (IVUS) studies have shown that biomechanical
variables, particularly endothelial shear stress (ESS), add synergistic prognostic insight …