The study of brain plasticity has tended to focus on the synapse, where well-described
activity-dependent mechanisms are known to play a key role in learning and memory …

Highlights•Physical activity is an effective method of capitalizing on brain plasticity.•Some
brain areas and cognitive domains are more consistently influenced by physical activity than …

Aerobic exercise improves cognitive and motor function by inducing neural changes
detected using molecular, cellular, and systems level neuroscience techniques. This review …

Physical activity (PA) is known to maintain and improve neurocognitive health. However,
there is still a poor understanding of the mechanisms by which PA exerts its effects on the …

This narrative review aimed to summarize evidence regarding the responses to exercise
among patients with preclinical Alzheimer's disease (AD) and the effectiveness of long-term …

Sedentary time (ST) is an important risk factor for a variety of health outcomes in older
adults. Consensus is needed on future research directions so that collaborative and timely …

The number of studies investigating exercise and cardiorespiratory fitness (CRF)-related
changes in the functional and structural organization of brain networks continues to rise …

Higher levels of physical fitness or activity (PFA) have been shown to have beneficial effects
on cognitive function and grey matter volumes in older adults. However, the relationship …

Despite increasing evidence that physical activity (PA) contributes to brain health in older
individuals, both at the level of brain structure and function, this relationship is not yet well …

Greater physical activity and cardiorespiratory fitness are associated with reduced age-
related cognitive decline and lower risk for dementia. However, significant gaps remain in …