Exploring target site interactions of 1, 3, 4-Oxadiazole/1, 3, 4-thiadiazole derivatives: Synthesis, characterization in vitro anti-urease and in silico molecular docking …

R Hussain, S Khan, W Rehman, Z Ullah, Y Khan… - Journal of Molecular …, 2025 - Elsevier
Urease enzyme is one of the major causes of severe health issues including urinary catheter
encrustation, gastric cancer, duodenal ulcer and peptic ulcer. In search for potent anti …

[HTML][HTML] Synthesis, docking and biological evaluation of thiadiazole and oxadiazole derivatives as antimicrobial and antioxidant agents

MJN Khadri, AB Begum, MK Sunil, SA Khanum - Results in Chemistry, 2020 - Elsevier
A series of potential biological active substituted thiadiazoles 5a-j and oxadiazoles 6a-j were
obtained via a multistep synthesis sequence with a simple and convenient approach by …

[PDF][PDF] Biological Activity

KC Parmar, NH Umrigar - Journal of Chemical and Pharmaceutical …, 2017 - academia.edu
The present review outlines the synthesis and different biological activities of 1, 3, 4
thiadiazole and its derivatives. 1, 3, 4 thiadiazole has been studied extensively because of …

Composition of 1, 3, 4-selenadiazole containing compounds with pharmacological activity

BH Ruan, JJ Ruan - US Patent 10,975,048, 2021 - Google Patents
The selenium-containing heterocycle has the efficacy of 20 Se antioxidant, anti-
inflammatory, antibacterial, antiviral and Cn1 antitumor activity. The anti-tumor mechanism of …

[PDF][PDF] Design, synthesis and evaluation of specific TNF-α inhibitory novel dithioic acid derivative from natural acids as anti-inflammatory agents

KP Deepu, B Thomas, J Harindran - Int J Pharm Chem, 2016 - researchgate.net
Novel dithioic acid derivatives have been synthesized from 3 different natural acids having
marked antiinflammatory activities including ferulic acid, cinnamic acid and salicylic acid …