Epigallocatechin 3-gallate: From green tea to cancer therapeutics
Abstract Epigallocatechin 3-gallate (EGCG) possesses various biological functions,
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer
A Negri, V Naponelli, F Rizzi, S Bettuzzi - Nutrients, 2018 - mdpi.com
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …
on different diseases, including cancer. The major components of green tea are catechins, a …
The compromise of virtual screening and its impact on drug discovery
O Slater, M Kontoyianni - Expert opinion on drug discovery, 2019 - Taylor & Francis
Introduction: Docking and structure-based virtual screening (VS) have been standard
approaches in structure-based design for over two decades. However, our understanding of …
approaches in structure-based design for over two decades. However, our understanding of …
Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode
The peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in
the regulation of the metabolic homeostasis and therefore represent valuable therapeutic …
the regulation of the metabolic homeostasis and therefore represent valuable therapeutic …
Peptide-modified chitosan hydrogels accelerate skin wound healing by promoting fibroblast proliferation, migration, and secretion
X Chen, M Zhang, S Chen, X Wang, Z Tian… - Cell …, 2017 - journals.sagepub.com
Skin wound healing is a complicated process that involves a variety of cells and cytokines.
Fibroblasts play an important role in this process and participate in transformation into …
Fibroblasts play an important role in this process and participate in transformation into …
Receptors that bind to PEDF and their therapeutic roles in retinal diseases
M Xu, X Chen, Z Yu, X Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Retinal neovascular, neurodegenerative, and inflammatory diseases represented by
diabetic retinopathy are the main types of blinding eye disorders that continually cause the …
diabetic retinopathy are the main types of blinding eye disorders that continually cause the …
SIKVAV-modified chitosan hydrogel as a skin substitutes for wound closure in mice
X Chen, X Cao, H Jiang, X Che, X Xu, B Ma, J Zhang… - Molecules, 2018 - mdpi.com
Skin wound healing is a complex and dynamic process that involves angiogenesis and
growth factor secretion. Newly formed vessels can provide nutrition and oxygen for skin …
growth factor secretion. Newly formed vessels can provide nutrition and oxygen for skin …
[HTML][HTML] Peptide-modified chitosan hydrogels promote skin wound healing by enhancing wound angiogenesis and inhibiting inflammation
X Chen, M Zhang, X Wang, Y Chen, Y Yan… - American journal of …, 2017 - ncbi.nlm.nih.gov
Cutaneous wound healing following trauma is a complex and dynamic process involving
multiple overlapping events following trauma. Two critical elements affecting skin wound …
multiple overlapping events following trauma. Two critical elements affecting skin wound …
The Cuticle Protein Gene MPCP4 of Myzus persicae (Homoptera: Aphididae) Plays a Critical Role in Cucumber Mosaic Virus Acquisition
Y Liang, XW Gao - Journal of economic entomology, 2017 - academic.oup.com
Abstract Myzus persicae (Sulzer)(Homoptera: Aphididae) is one of the most important
agricultural pests worldwide. In addition to sucking phloem sap, M. persicae also transmits …
agricultural pests worldwide. In addition to sucking phloem sap, M. persicae also transmits …
Flavonoid quercetin and its glucuronide and sulfate conjugates bind to 67-kDa laminin receptor and prevent neuronal cell death induced by serum starvation
R Gopalakrishna, A Oh, L Hou, E Lee, J Aguilar… - Biochemical and …, 2023 - Elsevier
Quercetin, a dietary flavonoid, has been shown to protect against various
neurodegenerative diseases with mechanisms largely unknown. After oral administration …
neurodegenerative diseases with mechanisms largely unknown. After oral administration …