Sulfonyl fluorides as targets and substrates in the development of new synthetic methods
The advent of sulfur (vi)-fluoride exchange (SuFEx) processes as transformations with click-
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …
The growing applications of SuFEx click chemistry
SuFEx (Sulfur Fluoride Exchange) is a modular, next generation family of click reactions,
geared towards the rapid and reliable assembly of functional molecules. This review …
geared towards the rapid and reliable assembly of functional molecules. This review …
Advances in the construction of diverse SuFEx linkers
D Zeng, WP Deng, X Jiang - National Science Review, 2023 - academic.oup.com
Sulfur fluoride exchange (SuFEx), a new generation of click chemistry, was first presented by
Sharpless, Dong and co-workers in 2014. Owing to the high stability and yet efficient …
Sharpless, Dong and co-workers in 2014. Owing to the high stability and yet efficient …
SuFExable polymers with helical structures derived from thionyl tetrafluoride
Sulfur (vi) fluoride exchange (SuFEx) is a category of click chemistry that enables covalent
linking of modular units through sulfur (vi) connective hubs. The efficiency of SuFEx and the …
linking of modular units through sulfur (vi) connective hubs. The efficiency of SuFEx and the …
Synthesis of chiral sulfonimidoyl chloride via desymmetrizing enantioselective hydrolysis
G Yang, Y Yuan, Y Tian, S Zhang, X Cui… - Journal of the …, 2023 - ACS Publications
Direct construction of chiral S (VI) from prochiral S (II) is a formidable challenge due to the
inevitable formation of stable chiral S (IV). Previous synthetic strategies rely on the …
inevitable formation of stable chiral S (IV). Previous synthetic strategies rely on the …
SuFEx click chemistry enabled late-stage drug functionalization
Sulfur (VI) Fluoride Exchange (SuFEx) is a new family of click chemistry transformations
which relies on readily available materials to produce compounds bearing the SVI–F motif …
which relies on readily available materials to produce compounds bearing the SVI–F motif …
Selective fluorosulfonylation of thianthrenium salts enabled by electrochemistry
X Kong, Y Chen, Q Liu, WJ Wang, S Zhang… - Organic …, 2023 - ACS Publications
A practical electrochemically driven method for fluorosulfonylation of both aryl and alkyl
thianthrenium salts has been disclosed. The strategy does not need external redox reagents …
thianthrenium salts has been disclosed. The strategy does not need external redox reagents …
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
Drug candidates that form covalent linkages with their target proteins have been
underexplored compared with the conventional counterparts that modulate biological …
underexplored compared with the conventional counterparts that modulate biological …
Divergent sulfur (VI) fluoride exchange linkage of sulfonimidoyl fluorides and alkynes
D Zeng, Y Ma, WP Deng, M Wang, X Jiang - Nature Synthesis, 2022 - nature.com
Sulfur (VI) fluoride exchange reactions have been applied to the linkage of a diverse range
of molecules. However, the connectivity of fluorosulfuryls with alkynes remains a formidable …
of molecules. However, the connectivity of fluorosulfuryls with alkynes remains a formidable …