Developmental programming, a pathway to disease

V Padmanabhan, RC Cardoso… - Endocrinology, 2016 - academic.oup.com
Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

The link between stress and feeding behaviour

J Maniam, MJ Morris - Neuropharmacology, 2012 - Elsevier
Exposure to stress is inevitable, and it may occur, to varying degrees, at different phases
throughout the lifespan. The impact of stress experienced in later life has been well …

K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

M Choi, UI Scholl, P Yue, P Björklund, B Zhao… - Science, 2011 - science.org
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of
severe hypertension, feature constitutive hormone production and unrestrained cell …

The developmental origins of health and disease (DOHaD) concept: past, present, and future

PD Gluckman, T Buklijas, MA Hanson - The epigenome and developmental …, 2016 - Elsevier
The “developmental origins of health and disease”(DOHaD) is a concept that has emerged
over the past 50 years, linking the state of health and risk from disease in later childhood …

The early origins of obesity and insulin resistance: timing, programming and mechanisms

LM Nicholas, JL Morrison, L Rattanatray… - International journal of …, 2016 - nature.com
Maternal obesity is associated with an increased risk of developing gestational diabetes
mellitus and it also results in an increased risk of giving birth to a large baby with increased …

Health management of ewes during pregnancy

GC Fthenakis, G Arsenos, C Brozos, IA Fragkou… - Animal reproduction …, 2012 - Elsevier
The objectives of health management of ewes during pregnancy are as follows:(i) successful
completion of pregnancy at term,(ii) birth of healthy and viable lambs, with optimal birth and …

Nutritional programming through broodstock diets to improve utilization of very low fishmeal and fish oil diets in gilthead sea bream

MS Izquierdo, S Turkmen, D Montero, MJ Zamorano… - Aquaculture, 2015 - Elsevier
The complete removal of fishmeal (FM) and fish oil (FO) is required to promote the
sustainable development of aquaculture and for that, fast growing high quality fish that are …

Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice

AJ Watkins, KD Sinclair - American Journal of Physiology …, 2014 - journals.physiology.org
Although the association between maternal periconceptional diet and adult offspring health
is well characterised, our understanding of the impact of paternal nutrition at the time of …

Embryos, DOHaD and david barker

TP Fleming, MA Velazquez, JJ Eckert - Journal of developmental …, 2015 - cambridge.org
The early embryo and periconceptional period is a window during which environmental
factors may cause permanent change in the pattern and characteristics of development …

Nutritional programming of insulin resistance: causes and consequences

DE Duque-Guimarães, SE Ozanne - Trends in Endocrinology & Metabolism, 2013 - cell.com
Strong evidence indicates that adverse prenatal and early postnatal environments have a
significant long-term influence on risk factors that result in insulin resistance, type 2 diabetes …