[HTML][HTML] Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

[HTML][HTML] Clinical application and detection techniques of liquid biopsy in gastric cancer

S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular Cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

A DNA-based hydrogel for exosome separation and biomedical applications

J Tang, X Jia, Q Li, Z Cui, A Liang… - Proceedings of the …, 2023 - National Acad Sciences
Exosomes (EXOs) have been proven as biomarkers for disease diagnosis and agents for
therapeutics. Great challenge remains in the separation of EXOs with high-purity and low …

Towards microfluidic-based exosome isolation and detection for tumor therapy

J Wang, P Ma, DH Kim, BF Liu, U Demirci - Nano Today, 2021 - Elsevier
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …

Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy

Y Liang, BM Lehrich, S Zheng… - Journal of Extracellular …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are released by many cell types and distributed within various
biofluids. EVs have a lipid membrane‐confined structure that allows for carrying unique …

The role of exosomes in liquid biopsy for cancer diagnosis and prognosis prediction

S Li, M Yi, B Dong, X Tan, S Luo… - International journal of …, 2021 - Wiley Online Library
Liquid biopsy is a revolutionary strategy in cancer diagnosis and prognosis prediction, which
is used to analyze cancer cells or cancer‐derived products through biofluids such as blood …

Mir-30d regulates cardiac remodeling by intracellular and paracrine signaling

J Li, AM Salvador, G Li, N Valkov, O Ziegler… - Circulation …, 2021 - Am Heart Assoc
Rationale: Previous translational studies implicate plasma extracellular microRNA-30d (miR-
30d) as a biomarker in left ventricular remodeling and clinical outcome in heart failure (HF) …

Simultaneous detection of tumor derived exosomal protein–microRNA pairs with an Exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

Direct quantification of cancerous exosomes via surface plasmon resonance with dual gold nanoparticle-assisted signal amplification

Q Wang, L Zou, X Yang, X Liu, W Nie, Y Zheng… - Biosensors and …, 2019 - Elsevier
Sensitive detection of cancerous exosomes is critical to early diseases diagnosis and
prognosis. Herein, a sensitive aptasensor was demonstrated for exosomes detection by …

[HTML][HTML] Recent progress in microRNA-based delivery systems for the treatment of human disease

Y Fu, J Chen, Z Huang - ExRNA, 2019 - Springer
MicroRNAs (miRNAs) are naturally occurring, small non-coding RNAs that mediate
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …