A comprehensive review of COVID-19 virology, vaccines, variants, and therapeutics

L Forchette, W Sebastian, T Liu - Current medical science, 2021 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …

Drug design by pharmacophore and virtual screening approach

D Giordano, C Biancaniello, MA Argenio, A Facchiano - Pharmaceuticals, 2022 - mdpi.com
Computer-aided drug discovery techniques reduce the time and the costs needed to
develop novel drugs. Their relevance becomes more and more evident with the needs due …

Roles of flavonoids against coronavirus infection

M Russo, S Moccia, C Spagnuolo, I Tedesco… - Chemico-biological …, 2020 - Elsevier
In terms of public health, the 21st century has been characterized by coronavirus
pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV emerged …

[HTML][HTML] Traditional Chinese medicine in COVID-19

M Lyu, G Fan, G Xiao, T Wang, D Xu, J Gao… - … Pharmaceutica Sinica B, 2021 - Elsevier
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread across the globe, posing an enormous threat to public health and safety …

Natural products' role against COVID-19

A da Silva Antonio, LSM Wiedemann… - RSC advances, 2020 - pubs.rsc.org
COVID-19 is a viral disease caused by a new severe acute respiratory syndrome (SARS-
CoV-2), which has quickly resulted in a pandemic. As a great threat to global public health …

In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2

BG Vijayakumar, D Ramesh, A Joji, T Kannan - European journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is distinctly infective and
there is an ongoing effort to find a cure for this pandemic. Flavonoids exist in many diets as …

Contributions of human ACE2 and TMPRSS2 in determining host–pathogen interaction of COVID-19

S Senapati, P Banerjee, S Bhagavatula… - Journal of genetics, 2021 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is at present an
emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans …

The looming effects of estrogen in Covid-19: a rocky rollout

HM Al-Kuraishy, AI Al-Gareeb, H Faidah… - Frontiers in …, 2021 - frontiersin.org
In the face of the Covid-19 pandemic, an intensive number of studies have been performed
to understand in a deeper way the mechanisms behind better or worse clinical outcomes …

Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches

M Gioia, C Ciaccio, P Calligari, G De Simone… - Biochemical …, 2020 - Elsevier
In the Fall of 2019 a sudden and dramatic outbreak of a pulmonary disease (Coronavirus
Disease COVID-19), due to a new Coronavirus strain (ie, SARS-CoV-2), emerged in the …

An enzymatic TMPRSS2 assay for assessment of clinical candidates and discovery of inhibitors as potential treatment of COVID-19

JH Shrimp, SC Kales, PE Sanderson… - ACS pharmacology & …, 2020 - ACS Publications
SARS-CoV-2 is the viral pathogen causing the COVID19 global pandemic. Consequently,
much research has gone into the development of preclinical assays for the discovery of new …