[HTML][HTML] Metabolic messengers: tumour necrosis factor

JK Sethi, GS Hotamisligil - Nature metabolism, 2021 - nature.com
Tumour necrosis factor (TNF) is a classical, pleiotropic pro-inflammatory cytokine. It is also
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …

[HTML][HTML] Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment

Q Yi, Z Xu, A Thakur, K Zhang, Q Liang, Y Liu… - Pharmacological …, 2023 - Elsevier
Natural compounds are widely used to prevent and treat various diseases due to their
antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant …

[HTML][HTML] The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment

Z Zhang, Y Yu, G Zhu, L Zeng, S Xu, H Cheng… - Frontiers in …, 2022 - frontiersin.org
Periodontitis is an infectious oral disease, which leads to the destruction of periodontal
tissues and tooth loss. Although the treatment of periodontitis has improved recently, the …

[HTML][HTML] Plant-derived extracellular vesicles (PDEVs) in nanomedicine for human disease and therapeutic modalities

Z Xu, Y Xu, K Zhang, Y Liu, Q Liang, A Thakur… - Journal of …, 2023 - Springer
Background The past few years have witnessed a significant increase in research related to
plant-derived extracellular vesicles (PDEVs) in biological and medical applications. Using …

Advances in bioactivity of microRNAs of plant-derived exosome-like nanoparticles and milk-derived extracellular vesicles

D Li, X Yao, J Yue, Y Fang, G Cao… - Journal of Agricultural …, 2022 - ACS Publications
MicroRNA (miRNA) is a class of small noncoding RNA involved in physiological and
pathological processes via the regulation of gene expression. Naked miRNAs are unstable …

Edible plant-derived exosomal microRNAs: Exploiting a cross-kingdom regulatory mechanism for targeting SARS-CoV-2

SP Kalarikkal, GM Sundaram - Toxicology and applied pharmacology, 2021 - Elsevier
Background The current COVID-19 pandemic is caused by SARS-CoV-2 which belongs to
coronaviridae family. Despite the global prevalence, there are currently no vaccines or …

Dendrobium officinale polysaccharide ameliorates the liver metabolism disorders of type II diabetic rats

J Yang, H Chen, Q Nie, X Huang, S Nie - International Journal of Biological …, 2020 - Elsevier
Abstract Type 2 diabetes (T2D) is a complicated endocrine metabolic disease, accompanied
with oxidative stress injury and low-grade inflammation. The effects of polysaccharide …

[HTML][HTML] Plant-derived nano and microvesicles for human health and therapeutic potential in nanomedicine

M Alfieri, A Leone, A Ambrosone - Pharmaceutics, 2021 - mdpi.com
Plants produce different types of nano and micro-sized vesicles. Observed for the first time in
the 60s, plant nano and microvesicles (PDVs) and their biological role have been …

[HTML][HTML] Potential mechanisms linking food-derived microRNAs, gut microbiota and intestinal barrier functions in the context of nutrition and human health

E Díez-Sainz, S Lorente-Cebrián, P Aranaz… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules from 18 to 24
nucleotides that are produced by prokaryote and eukaryote organisms, which play a crucial …

[HTML][HTML] Plant-RNA in extracellular vesicles: the secret of cross-kingdom communication

O Urzì, R Gasparro, NR Ganji, R Alessandro… - Membranes, 2022 - mdpi.com
The release of extracellular vesicles (EVs) is a common language, used by living organisms
from different kingdoms as a means of communication between them. Extracellular vesicles …