Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

The Ras superfamily of small GTPases are guanine‐nucleotide‐dependent switches
essential for numerous cellular processes. Mutations or dysregulation of these proteins are …

Herein, we report a cobalt N, N-bidentate complex catalyzed reductive formylation of N-
heteroarenes for the generation of N-formyltetrahydroquinoline (FTHQ) derivatives, formic …

N-doped nestlike carbon nanosheets (NCNs-N x) were prepared successfully by a two-step
strategy, namely, the in situ self-assembly hydrothermal synthesis using glucose as the …

Mycosporine-like amino acids (MAAs) are water-soluble metabolites, reported to exhibit
strong UV-absorbing properties. They have been found in a wide range of marine …

Selective functionalization has numerous potential applications in the modification of
bioactive compounds and pharmaceuticals. Herein, we advance a new approach for the …

In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary
messenger, and the first signaling cascade discovered was the cAMP-protein kinase A …

Classical uncompetitive inhibitors are potent pharmacological modulators of enzyme
function. Since they selectively target enzyme–substrate complexes (E: S), their inhibitory …

Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity
(spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate …

The universal second messenger cAMP regulates diverse intracellular processes by
interacting with ubiquitously expressed proteins, such as Protein Kinase A (PKA) and the …