Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

L Smigielski, V Jagannath, W Rössler, S Walitza… - Molecular …, 2020 - nature.com
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability

J Richetto, U Meyer - Biological Psychiatry, 2021 - Elsevier
Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

DNA methylation and schizophrenia: current literature and future perspective

T Magwai, KB Shangase, FO Oginga, B Chiliza… - Cells, 2021 - mdpi.com
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

Epigenetics of schizophrenia

A Srivastava, O Dada, J Qian, N Al-Chalabi… - Psychiatry …, 2021 - Elsevier
Schizophrenia (SCZ) is a chronic psychotic disorder that contributes significantly to
disability, affecting behavior, thought, and cognition. It has long been known that there is a …

Can epigenetics shine a light on the biological pathways underlying major mental disorders?

L Alameda, G Trotta, H Quigley, V Rodriguez… - Psychological …, 2022 - cambridge.org
A significant proportion of the global burden of disease can be attributed to mental illness.
Despite important advances in identifying risk factors for mental health conditions, the …

Targeting DNA methylation in the adult brain through diet

J Allison, A Kaliszewska, S Uceda, M Reiriz, N Arias - Nutrients, 2021 - mdpi.com
Metabolism and nutrition have a significant role in epigenetic modifications such as DNA
methylation, which can influence gene expression. Recently, it has been suggested that …

DNA methylation as a predictor of fetal alcohol spectrum disorder

AA Lussier, AM Morin, JL MacIsaac, J Salmon… - Clinical …, 2018 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a developmental disorder that
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …

Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia

C Chen, C Zhang, L Cheng, JL Reilly… - Bipolar …, 2014 - Wiley Online Library
Objectives Aberrant DNA methylation and gene expression have been reported in
postmortem brain tissues of psychotic patients, but until now there has been no systematic …

DNA methylation and psychiatric disorders

C Liu, C Jiao, K Wang, N Yuan - Progress in molecular biology and …, 2018 - Elsevier
DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …

Understanding epigenetics of schizophrenia in the backdrop of its antipsychotic drug therapy

B Swathy, M Banerjee - Epigenomics, 2017 - Taylor & Francis
The diatheses of gene and environment interaction in schizophrenia (SCZ) are becoming
increasingly evident. Genetic and epigenetic backgrounds are being considered in …