[HTML][HTML] Understanding treatment tolerability in older adults with cancer
MA Flannery, E Culakova, BE Canin… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The treatment cannot be worse than the disease is an oft-cited statement representing the
important concept of tolerability; older patients often express concerns about side effects …
important concept of tolerability; older patients often express concerns about side effects …
Treatment regimens for transplant-ineligible patients with newly diagnosed multiple myeloma: a systematic literature review and network meta-analysis
Introduction Many treatment regimens have been evaluated in transplant-ineligible (TIE)
patients with newly diagnosed multiple myeloma (NDMM). The objective of this study was to …
patients with newly diagnosed multiple myeloma (NDMM). The objective of this study was to …
Addition of elotuzumab to lenalidomide and dexamethasone for patients with newly diagnosed, transplantation ineligible multiple myeloma (ELOQUENT-1): an open …
MA Dimopoulos, PG Richardson, NJ Bahlis… - The Lancet …, 2022 - thelancet.com
Background Elotuzumab plus lenalidomide and dexamethasone has shown improved
progression-free and overall survival versus lenalidomide and dexamethasone in patients …
progression-free and overall survival versus lenalidomide and dexamethasone in patients …
A comprehensive approach to therapy of haematological malignancies in older patients
Haematological malignancies are a heterogeneous group of diseases with diverse
incidence. In Europe, the median age at diagnosis across all disease entities is 69 years …
incidence. In Europe, the median age at diagnosis across all disease entities is 69 years …
Cost-effectiveness of first-line versus second-line use of daratumumab in older, transplant-ineligible patients with multiple myeloma
PURPOSE The MAIA trial found that addition of daratumumab to lenalidomide and
dexamethasone (DRd) significantly prolonged progression-free survival in transplant …
dexamethasone (DRd) significantly prolonged progression-free survival in transplant …
[HTML][HTML] Efficacy of first-line treatment options in transplant-ineligible multiple myeloma: A network meta-analysis
S Kiss, N Gede, A Soos, P Hegyi, B Nagy… - Critical Reviews in …, 2021 - Elsevier
Background Despite major therapeutic advances, the rational choice of the most appropriate
first-line regimen in newly diagnosed transplant-ineligible multiple myeloma (TIE-MM) is …
first-line regimen in newly diagnosed transplant-ineligible multiple myeloma (TIE-MM) is …
Role of daratumumab in the frontline management of multiple myeloma: a narrative review
S Yadav, S Gundeti, A Bhave, U Deb… - Expert Review of …, 2023 - Taylor & Francis
Introduction The prevalence of multiple myeloma (MM) has gradually increased over the last
few decades in India due to growing population, better disease awareness, and improved …
few decades in India due to growing population, better disease awareness, and improved …
Transplant-ineligible newly diagnosed multiple myeloma: Current and future approaches to clinical care: A Young International Society of Geriatric Oncology Review …
Multiple myeloma is the second most common hematological malignancy in the USA and
Europe. Despite improvements in the 5-year and overall survival rates over the past decade …
Europe. Despite improvements in the 5-year and overall survival rates over the past decade …
[HTML][HTML] 达雷妥尤单抗在多发性骨髓瘤中的应用
贺玉钦, 陈文明 - 临床血液学杂志, 2023 - lcxy.whuhzzs.com
达雷妥尤单抗是一种新型人源化抗CD38 单克隆抗体, 可靶向治疗多发性骨髓瘤(multiple
myeloma, MM) 瘤细胞表面的CD38, 直接杀伤肿瘤细胞和通过调节免疫微环境双重作用机制 …
myeloma, MM) 瘤细胞表面的CD38, 直接杀伤肿瘤细胞和通过调节免疫微环境双重作用机制 …
Network meta‐analysis of randomized trials in multiple myeloma: Efficacy and safety in frontline therapy for patients not eligible for transplant
C Botta, E Gigliotta, B Paiva, R Anselmo… - Hematological …, 2022 - Wiley Online Library
The treatment scenario for newly‐diagnosed transplant‐ineligible multiple myeloma patients
(NEMM) is quickly evolving. Currently, combinations of proteasome inhibitors and/or …
(NEMM) is quickly evolving. Currently, combinations of proteasome inhibitors and/or …