Combating implant infections: shifting focus from bacteria to host

S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Interaction between nanomaterials and the innate immune system across evolution

D Boraschi, L Canesi, D Drobne… - Biological …, 2023 - Wiley Online Library
Interaction of engineered nanomaterials (ENMs) with the immune system mainly occurs with
cells and molecules of innate immunity, which are present in interface tissues of living …

Overcoming multidrug resistance of antibiotics via nanodelivery systems

M Imran, SK Jha, N Hasan, A Insaf, J Shrestha… - Pharmaceutics, 2022 - mdpi.com
Antibiotic resistance has become a threat to microbial therapies nowadays. The
conventional approaches possess several limitations to combat microbial infections …

Immunotoxicity of nanomaterials in health and disease: Current challenges and emerging approaches for identifying immune modifiers in susceptible populations

S Hofer, N Hofstätter, B Punz… - Wiley …, 2022 - Wiley Online Library
Nanosafety assessment has experienced an intense era of research during the past
decades driven by a vivid interest of regulators, industry, and society. Toxicological assays …

Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment

F Lebre, N Chatterjee, S Costa… - Nanomaterials, 2022 - mdpi.com
The use of nanomaterials has been increasing in recent times, and they are widely used in
industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid …

Addressing nanomaterial immunosafety by evaluating innate immunity across living species

D Boraschi, A Alijagic, M Auguste, F Barbero, E Ferrari… - Small, 2020 - Wiley Online Library
The interaction of a living organism with external foreign agents is a central issue for its
survival and adaptation to the environment. Nanosafety should be considered within this …

Immunotherapeutic nanoparticles: From autoimmune disease control to the development of vaccines

R Mitarotonda, E Giorgi, T Eufrasio-da-Silva… - Biomaterials …, 2022 - Elsevier
The development of nanoparticles (NPs) with potential therapeutic uses represents an area
of vast interest in the scientific community during the last years. Recently, the pandemic …

Immunomodulation, toxicity, and therapeutic potential of nanoparticles

A Pandey, AK Mishra - BioTech, 2022 - mdpi.com
Altered immune responses associated with human disease conditions, such as inflammatory
and infectious diseases, cancers, and autoimmune diseases, are among the primary causes …

Breaking the barrier: Nanoparticle-enhanced radiotherapy as the new vanguard in brain tumor treatment

S Liu, MJ Li, B Liang, W Sun, Y Shao, X Hu… - Frontiers in …, 2024 - frontiersin.org
The pursuit of effective treatments for brain tumors has increasingly focused on the
promising area of nanoparticle-enhanced radiotherapy (NERT). This review elucidates the …

Impact of gold nanoparticles on the functions of macrophages and dendritic cells

AK Dey, A Gonon, EI Pécheur, M Pezet, C Villiers… - Cells, 2021 - mdpi.com
Gold nanoparticles (AuNPs) have demonstrated outstanding performance in many
biomedical applications. Their safety is recognised; however, their effects on the immune …