Obesity has been well recognized as an important comorbidity in patients with asthma,
representing a unique phenotype and endotype. This association indicates a close …

Obesity is currently one of the major epidemics of this millennium and affects individuals
throughout the world. It causes multiple systemic complications, some of which result in …

Obesity and asthma are two chronic conditions that affect millions of people. Genetic and
lifestyle factors such as diet, physical activity, and early exposure to micro-organisms are …

Biomarkers have been critical for studies of disease pathogenesis and the development of
new therapies in severe asthma. In particular, biomarkers of type 2 inflammation have …

Background Obesity is a common comorbidity in asthma and associated with poorer asthma
control, more frequent/severe exacerbations, and reduced response to asthma …

Obesity and asthma are associated with systemic inflammation maintained by mediators
released by adipose tissue and lung. This study investigated the inflammatory serum …

Adiponectin is an adipokine associated with the healthy obese phenotype. Adiponectin
increases insulin sensitivity and has cardio and vascular protection actions. Studies related …

Background Obesity is associated with more severe asthma, however, the mechanisms
responsible are poorly understood. Obesity is also associated with low-grade systemic …

The hallmarks of systemic sclerosis (SSc) are autoimmunity, microangiopathy and fibrosis.
Skin fibrosis is accompanied by attrition of the dermal white adipose tissue layer, and …

IL‐33 is a recently discovered cytokine which plays an important role in asthma
pathogenesis. Aim To evaluate serum IL‐33 in patients with asthma and healthy controls …