Ductal carcinoma in situ: to treat or not to treat, that is the question
M van Seijen, EH Lips, AM Thompson… - British journal of …, 2019 - nature.com
Ductal carcinoma in situ (DCIS) now represents 20–25% of all 'breast cancers' consequent
upon detection by population-based breast cancer screening programmes. Currently, all …
upon detection by population-based breast cancer screening programmes. Currently, all …
Ductal carcinoma in situ: state-of-the-art review
Ductal carcinoma in situ (DCIS) is a nonobligate precursor of invasive cancer, and its
detection, diagnosis, and management are controversial. DCIS incidence grew with the …
detection, diagnosis, and management are controversial. DCIS incidence grew with the …
Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer
EH Lips, T Kumar, A Megalios, LL Visser… - Nature …, 2022 - nature.com
Ductal carcinoma in situ (DCIS) is the most common form of preinvasive breast cancer and,
despite treatment, a small fraction (5–10%) of DCIS patients develop subsequent invasive …
despite treatment, a small fraction (5–10%) of DCIS patients develop subsequent invasive …
The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in …
ES Hwang, T Hyslop, T Lynch, E Frank, D Pinto… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Ductal carcinoma in situ (DCIS) is a non-invasive non-obligate precursor of
invasive breast cancer. With guideline concordant care (GCC), DCIS outcomes are at least …
invasive breast cancer. With guideline concordant care (GCC), DCIS outcomes are at least …
The immune microenvironment of breast cancer progression
H Tower, M Ruppert, K Britt - Cancers, 2019 - mdpi.com
Inflammation is now recognized as a hallmark of cancer. Genetic changes in the cancer cell
are accepted as the match that lights the fire, whilst inflammation is seen as the fuel that …
are accepted as the match that lights the fire, whilst inflammation is seen as the fuel that …
Cancer outcomes in DCIS patients without locoregional treatment
Background The vast majority of women diagnosed with ductal carcinoma in situ (DCIS)
undergo treatment. Therefore, the risks of invasive progression and competing death in the …
undergo treatment. Therefore, the risks of invasive progression and competing death in the …
Tailoring breast cancer screening intervals by breast density and risk for women aged 50 years or older: collaborative modeling of screening outcomes
A Trentham-Dietz, K Kerlikowske, NK Stout… - Annals of internal …, 2016 - acpjournals.org
Background: Biennial screening is generally recommended for average-risk women aged
50 to 74 years, but tailored screening may provide greater benefits. Objective: To estimate …
50 to 74 years, but tailored screening may provide greater benefits. Objective: To estimate …
Pathological features of 11,337 patients with primary ductal carcinoma in situ (DCIS) and subsequent events: results from the UK Sloane Project
AM Shaaban, B Hilton, K Clements… - British journal of …, 2021 - nature.com
Abstract Background The Sloane audit compares screen-detected ductal carcinoma in situ
(DCIS) pathology with subsequent management and outcomes. Methods This was a …
(DCIS) pathology with subsequent management and outcomes. Methods This was a …
Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ
M Tokura, J Nakayama, M Prieto-Vila, S Shiino… - Cancer Research, 2022 - AACR
Ductal carcinoma in situ (DCIS) is a precursor to invasive breast cancer. The frequency of
DCIS is increasing because of routine mammography; however, the biological features and …
DCIS is increasing because of routine mammography; however, the biological features and …
Association of DCIS size and margin status with risk of developing breast cancer post-treatment: multinational, pooled cohort study
RSJM Schmitz, AW van den Belt-Dusebout… - bmj, 2023 - bmj.com
Objective To examine the association between size and margin status of ductal carcinoma in
situ (DCIS) and risk of developing ipsilateral invasive breast cancer and ipsilateral DCIS …
situ (DCIS) and risk of developing ipsilateral invasive breast cancer and ipsilateral DCIS …