Analytical characteristics of high-sensitivity cardiac troponin assays

FS Apple, PO Collinson… - Clinical …, 2012 - academic.oup.com
Abstract BACKGROUND Cardiac troponins I (cTnI) and T (cTnT) have received international
endorsement as the standard biomarkers for detection of myocardial injury, for risk …

High-sensitivity cardiac troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guidelines for the evaluation and diagnosis of acute chest pain

Y Sandoval, FS Apple, SA Mahler, R Body… - Circulation, 2022 - Am Heart Assoc
The 2021 American Heart Association/American College of Cardiology/American Society of
Echocardiography/American College of Chest Physicians/Society for Academic Emergency …

How to use high-sensitivity cardiac troponins in acute cardiac care

K Thygesen, J Mair, E Giannitsis, C Mueller… - European heart …, 2012 - academic.oup.com
Recommendations for the use of cardiac troponin (cTn) measurement in acute cardiac care
have recently been published. 1 Subsequently, a high-sensitivity (hs) cTn T assay was …

Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population

FS Apple, R Ler, MAM Murakami - Clinical chemistry, 2012 - academic.oup.com
BACKGROUND Between-assay comparability of 99th percentiles for cardiac troponin
concentrations has not been assessed systematically in a single population for a large …

A comprehensive appraisal of laboratory biochemistry tests as major predictors of COVID-19 severity

E Aloisio, M Chibireva, L Serafini… - … of pathology & …, 2020 - meridian.allenpress.com
Context.—A relevant portion of coronavirus disease 2019 (COVID-19) patients develop
severe disease with negative outcomes. Several biomarkers have been proposed to predict …

Age-and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay

MO Gore, SL Seliger, CR Defilippi, V Nambi… - Journal of the American …, 2014 - jacc.org
Objectives: The study sought to determine the 99th percentile upper reference limit for the
high-sensitivity cardiac troponin T assay (hs-cTnT) in 3 large independent cohorts …

High-sensitivity assays for troponin in patients with cardiac disease

D Westermann, JT Neumann, NA Sörensen… - Nature Reviews …, 2017 - nature.com
Troponin is a widely used biomarker in patients with cardiac disease. The use of troponin is
well established in patients with suspected acute myocardial infarction (AMI), but troponin …

How to interpret elevated cardiac troponin levels

VS Mahajan, P Jarolim - Circulation, 2011 - Am Heart Assoc
The National Academy of Clinical Biochemistry issued a guideline in 2007 that stated that “in
the presence of a clinical history suggestive of ACS, the following is considered indicative of …

Cardiac troponin level elevations not related to acute coronary syndromes

E Giannitsis, HA Katus - Nature reviews cardiology, 2013 - nature.com
Over the past 2 decades, cardiac troponins (cTn) have emerged as the preferred biomarkers
for the noninvasive detection of myocardial injury. In conjunction with typical clinical findings …

Temporal release of high-sensitivity cardiac troponin T and I and copeptin after brief induced coronary artery balloon occlusion in humans

Á Árnadóttir, S Pedersen, R Bo Hasselbalch… - Circulation, 2021 - Am Heart Assoc
Background: Cardiac troponins (cTns) are the cornerstone of diagnosing acute myocardial
infarction. There is limited knowledge on the duration of ischemia necessary to induce a …