Determinants for the development of visceral leishmaniasis disease
LI McCall, WW Zhang, G Matlashewski - PLoS pathogens, 2013 - journals.plos.org
Leishmaniasis is a vector-borne neglected tropical disease associated with a spectrum of
clinical manifestations, ranging from self-healing cutaneous lesions to fatal visceral …
clinical manifestations, ranging from self-healing cutaneous lesions to fatal visceral …
Gene expression regulation in trypanosomatids
JG De Gaudenzi, G Noé, VA Campo… - Essays in …, 2011 - portlandpress.com
Trypanosomatids are protozoan micro-organisms that cause serious health problems in
humans and domestic animals. In addition to their medical relevance, these pathogens have …
humans and domestic animals. In addition to their medical relevance, these pathogens have …
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species
F Raymond, S Boisvert, G Roy, JF Ritt… - Nucleic acids …, 2012 - academic.oup.com
Abstract The Leishmania tarentolae Parrot-TarII strain genome sequence was resolved to an
average 16-fold mean coverage by next-generation DNA sequencing technologies. This is …
average 16-fold mean coverage by next-generation DNA sequencing technologies. This is …
Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum
P Leprohon, D Legare, F Raymond… - Nucleic acids …, 2009 - academic.oup.com
Antimonials remain the first line drug against the protozoan parasite Leishmania but their
efficacy is threatened by resistance. We carried out a RNA expression profiling analysis …
efficacy is threatened by resistance. We carried out a RNA expression profiling analysis …
The Genome Sequence of Leishmania (Leishmania) amazonensis: Functional Annotation and Extended Analysis of Gene Models
We present the sequencing and annotation of the Leishmania (Leishmania) amazonensis
genome, an etiological agent of human cutaneous leishmaniasis in the Amazon region of …
genome, an etiological agent of human cutaneous leishmaniasis in the Amazon region of …
Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels
B Mittra, M Cortez, A Haydock, G Ramasamy… - Journal of Experimental …, 2013 - rupress.org
During its life cycle, Leishmania undergoes extreme environmental changes, alternating
between insect vectors and vertebrate hosts. Elevated temperature and decreased pH …
between insect vectors and vertebrate hosts. Elevated temperature and decreased pH …
Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage
SA Iantorno, C Durrant, A Khan, MJ Sanders… - MBio, 2017 - Am Soc Microbiol
Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the
Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous …
Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous …
Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions
LAL Dillon, R Suresh, K Okrah, H Corrada Bravo… - BMC genomics, 2015 - Springer
Background Parasites of the genus Leishmania are the causative agents of leishmaniasis, a
group of diseases that range in manifestations from skin lesions to fatal visceral disease …
group of diseases that range in manifestations from skin lesions to fatal visceral disease …
The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi
TA Minning, DB Weatherly, J Atwood, R Orlando… - BMC genomics, 2009 - Springer
Background Chronic chagasic cardiomyopathy is a debilitating and frequently fatal outcome
of human infection with the protozoan parasite, Trypanosoma cruzi. Microarray analysis of …
of human infection with the protozoan parasite, Trypanosoma cruzi. Microarray analysis of …
Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation
LAL Dillon, K Okrah, VK Hughitt, R Suresh… - Nucleic acids …, 2015 - academic.oup.com
Protozoan parasites of the genus Leishmania are the etiological agents of leishmaniasis, a
group of diseases with a worldwide incidence of 0.9–1.6 million cases per year. We used …
group of diseases with a worldwide incidence of 0.9–1.6 million cases per year. We used …