Parkinson's disease (PD) is characterized by neurodegeneration of nigral-striatal neurons in
parallel with the formation of intra-neuronal α-synuclein aggregates, and these processes …

Microglia, the intrinsic neuroimmune cells residing in the central nervous system (CNS),
exert a pivotal influence on brain development, homeostasis, and functionality …

Background: The overexpression, accumulation, and cell-to-cell transmission of α-synuclein
leads to the deterioration of Parkinson's disease (PD). Previous studies suggest that …

Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung
disease. This study aimed to investigate the involvement of endoplasmic reticulum stress …

Aggregation of alpha-Synuclein (αSyn) has been connected to several neurodegenerative
diseases, such as Parkinson's disease (PD), dementia with Lewy Bodies (DLB), and multiple …

Background Parkinson's disease (PD) is a neurodegenerative condition characterized by
the loss of dopaminergic neurons and the accumulation of Lewy-body protein aggregates …

Neurodegenerative diseases are an increasingly common group of diseases that occur late
in life with a significant impact on personal, family, and economic life. Among these …

Parkinson's disease (PD) is the second most common neurodegenerative disease caused
by the loss of dopaminergic neurons. Genetic factors, inflammatory responses, oxidative …

Background: Microbial dysbiosis may contribute to alpha-synuclein (α-Syn) homeostasis
disruption, yet the burden of inflammatory periodontal infection and its treatment have never …

Synucleins are a family of proteins consisting of α, β, and γ synuclein (syn). The first syn was
discovered in the fish Torpedo californica [1], and subsequently syn isoforms were detected …