[HTML][HTML] A unique circulating microRNA pairs signature serves as a superior tool for early diagnosis of pan-cancer

P Wu, D Li, C Zhang, B Dai, X Tang, J Liu, Y Wu… - Cancer Letters, 2024 - Elsevier
Cancer remains a major burden globally and the critical role of early diagnosis is self-
evident. Although various miRNA-based signatures have been developed in past decades …

[HTML][HTML] Machine learning–based integration develops a stress response stated T cell (Tstr)–related score for predicting outcomes in clear cell renal cell carcinoma

S Yang, Z Han, Z Tan, Z Wu, J Ye, S Cai, Y Feng… - International …, 2024 - Elsevier
Background Establishment of a reliable prognostic model and identification of novel
biomarkers are urgently needed to develop precise therapy strategies for clear cell renal cell …

Decipher: A computational pipeline to extract context-specific mechanistic insights from single-cell profiles

EA Basto Piamonte, B Wajid, J Read, J Armitage… - bioRxiv, 2024 - biorxiv.org
The advent of single-cell profiling technologies has revolutionized our understanding of the
cellular and molecular states that underpin disease states and response to therapies …

[HTML][HTML] TimiGP: An R package to depict the tumor microenvironment from bulk transcriptomics

C Li, J Zhang, C Cheng - STAR protocols, 2023 - Elsevier
Exploring the clinical relevance of diverse immune cell types within the tumor
microenvironment is pivotal for unraveling cancer intricacies and developing treatments …