Stimulus-responsive sequential release systems for drug and gene delivery

S Ahmadi, N Rabiee, M Bagherzadeh, F Elmi, Y Fatahi… - Nano today, 2020 - Elsevier
In recent years, a range of studies have been conducted with the aim to design and
characterize delivery systems that are able to release multiple therapeutic agents in …

[HTML][HTML] Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world

M Prasad, UP Lambe, B Brar, I Shah… - Biomedicine & …, 2018 - Elsevier
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …

Near-infrared light-initiated molecular superoxide radical generator: rejuvenating photodynamic therapy against hypoxic tumors

M Li, J Xia, R Tian, J Wang, J Fan, J Du… - Journal of the …, 2018 - ACS Publications
Hypoxia, a quite universal feature in most solid tumors, has been considered as the
“Achilles' heel” of traditional photodynamic therapy (PDT) and substantially impairs the …

Superoxide radical photogenerator with amplification effect: surmounting the achilles' heels of photodynamic oncotherapy

M Li, T Xiong, J Du, R Tian, M Xiao, L Guo… - Journal of the …, 2019 - ACS Publications
Strong oxygen dependence, poor tumor targeting, and limited treatment depth have been
considered as the “Achilles' heels” facing the clinical usage of photodynamic therapy (PDT) …

Overcoming the limits of hypoxia in photodynamic therapy: a carbonic anhydrase IX-targeted approach

HS Jung, J Han, H Shi, S Koo, H Singh… - Journal of the …, 2017 - ACS Publications
A major challenge in photodynamic cancer therapy (PDT) is avoiding PDT-induced hypoxia,
which can lead to cancer recurrence and progression through activation of various …

Targeted cross-linker delivery for the in situ mapping of protein conformations and interactions in mitochondria

Y Chen, W Zhou, Y Xia, W Zhang, Q Zhao, X Li… - Nature …, 2023 - nature.com
Current methods for intracellular protein analysis mostly require the separation of specific
organelles or changes to the intracellular environment. However, the functions of proteins …

Using X-rays in photodynamic therapy: an overview

L Larue, AB Mihoub, Z Youssef, L Colombeau… - Photochemical & …, 2018 - pubs.rsc.org
Photodynamic therapy is a therapeutic option to treat cancer and other diseases. PDT is
used every day in dermatology, and recent developments in the treatment of glioblastoma …

Recent developments in nanomaterials-based drug delivery and upgrading treatment of cardiovascular diseases

NA Mohamed, I Marei, S Crovella… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality
worldwide. However, despite the recent developments in the management of CVDs, the …

Development of (−)-epigallocatechin-3-gallate-loaded folate receptor-targeted nanoparticles for prostate cancer treatment

RF Alserihi, MRS Mohammed, M Kaleem… - Nanotechnology …, 2021 - degruyter.com
In continuation of our previous studies, we developed polymeric epigallocatechin 3-gallate
(EGCG)-loaded nanoparticles (NPs) coupled with folic acid (FA), able to dually bind the …

Nanomaterials engineering for drug delivery: a hybridization approach

MR Mohammadi, A Nojoomi, M Mozafari… - Journal of Materials …, 2017 - pubs.rsc.org
The last twenty years have witnessed great advances in biology, medicine, and materials
science, leading to the development of various nanoparticle (NP)-mediated drug delivery …