Global burden of heart failure: a comprehensive and updated review of epidemiology

G Savarese, PM Becher, LH Lund… - Cardiovascular …, 2022 - academic.oup.com
Heart Failure (HF) is a multi-faceted and life-threatening syndrome characterized by
significant morbidity and mortality, poor functional capacity and quality of life, and high costs …

Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies

S de Wit, C Glen, RA de Boer… - Cardiovascular …, 2022 - academic.oup.com
Heart failure (HF) and cancer are the leading causes of death worldwide and accumulating
evidence demonstrates that HF and cancer affect one another in a bidirectional way …

Cancer incidence and mortality according to pre-existing heart failure in a community-based cohort

E Bertero, F Robusto, E Rulli, A D'Ettorre, L Bisceglia… - Cardio Oncology, 2022 - jacc.org
Background Studies assessing whether heart failure (HF) is associated with cancer and
cancer-related mortality have yielded conflicting results. Objectives This study assessed …

Cardiovascular disease and cancer: shared risk factors and mechanisms

NS Wilcox, U Amit, JB Reibel, E Berlin… - Nature Reviews …, 2024 - nature.com
Cardiovascular disease (CVD) and cancer are among the leading causes of morbidity and
mortality globally, and these conditions are increasingly recognized to be fundamentally …

Association between heart failure and the incidence of cancer: a systematic review and meta-analysis

V Jaiswal, SP Ang, V Agrawal… - … Heart Journal Open, 2023 - academic.oup.com
Aims The association between heart failure (HF) patients and the incidence of cancer is not
well understood, with conflicting results to date. The aim of this meta-analysis was to …

Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure

TG Gergely, ZD Drobni, M Kallikourdis, H Zhu… - Nature Reviews …, 2024 - nature.com
Immune checkpoint molecules are physiological regulators of the adaptive immune
response. Immune checkpoint inhibitors (ICIs), such as monoclonal antibodies targeting …

Integrin beta-like 1 mediates fibroblast–cardiomyocyte crosstalk to promote cardiac fibrosis and hypertrophy

XQ Chen, XT Li, XY Wu, Y Ding, Y Li… - Cardiovascular …, 2023 - academic.oup.com
Aims Crosstalk between fibroblasts and cardiomyocytes (CMs) plays a critical role in cardiac
remodelling during heart failure (HF); however, the underlying molecular mechanisms …

Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence

NV Sayour, ÁM Paál, P Ameri, WC Meijers… - European Heart …, 2024 - academic.oup.com
Heart failure (HF) patients have a significantly higher risk of new-onset cancer and cancer-
associated mortality, compared to subjects free of HF. While both the prevention and …

A review of research on the intersection between breast cancer and cardiovascular research in the Women's Health Initiative (WHI)

S Raychaudhuri, CM Dieli-Conwright, RK Cheng… - Frontiers in …, 2023 - frontiersin.org
Both obesity and metabolic syndrome are linked to increased incidence of type 2 diabetes,
cardiovascular disease (CVD), and cancers of the breast (post-menopausal), and other …

Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer?

S Mędrek, S Szmit - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Many factors contribute to mortality in lung cancer, including the presence of concomitant
cardiovascular disease. In the treatment of early stage of lung cancer, the presence of …