Muscle weakness and fatigue are the hallmarks of autoimmune neuromuscular junction
disorders. Although a plethora of immunosuppressive treatments exist, no cure is available …

Autoimmunity refers to the phenomenon that the body's immune system produces antibodies
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
underpinned by partially understood genetic risk factors and environmental triggers and …

ANPELA is widely used for quantifying traditional bulk proteomic data. Recently, there is a
clear shift from bulk proteomics to the single‐cell ones (SCP), for which powerful cytometry …

Group 1 innate lymphoid cells (ILCs) comprising circulating natural killer (cNK) cells and
tissue-resident ILC1s are critical for host defense against pathogens and tumors. Despite a …

The invasion of immune cells into the central nervous system (CNS) is a hallmark of the
process we call neuroinflammation. Diseases such as encephalitides or multiple sclerosis …

Myasthenia gravis (MG) is an autoimmune disorder that affects the neuromuscular junction,
leading to muscle weakness and fatigue. MG is caused by antibodies against the …

Abstract Interleukin-23 (IL-23) is a proinflammatory cytokine mainly produced by myeloid
cells that promotes tumor growth in various preclinical cancer models and correlates with …

The role of granulocyte-macrophage colony-stimulating factor (GM-CSF) was sequentially
redefined during the past decades. Originally described as a hematopoietic growth factor for …

Psoriasis is a chronic inflammatory skin disorder underpinned by dysregulated cytokine
signaling. Drugs neutralizing the common p40 subunit of interleukin-12 (IL-12) and IL-23 …