Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has led to an unprecedented effort toward the development of an effective …
(SARS-CoV-2) has led to an unprecedented effort toward the development of an effective …
Chemically engineered immune cell‐derived microrobots and biomimetic nanoparticles: emerging biodiagnostic and therapeutic tools
Over the past decades, considerable attention has been dedicated to the exploitation of
diverse immune cells as therapeutic and/or diagnostic cell‐based microrobots for hard‐to …
diverse immune cells as therapeutic and/or diagnostic cell‐based microrobots for hard‐to …
Direct in vivo activation of T cells with nanosized immunofilaments inhibits tumor growth and metastasis
L Weiss, J Weiden, Y Dölen, EM Grad… - Acs Nano, 2023 - ACS Publications
Adoptive T cell therapy has successfully been implemented for the treatment of cancer.
Nevertheless, ex vivo expansion of T cells by artificial antigen-presenting cells (aAPCs) …
Nevertheless, ex vivo expansion of T cells by artificial antigen-presenting cells (aAPCs) …
[HTML][HTML] SARS-CoV-2 vaccines: A critical perspective through efficacy data and barriers to herd immunity
Non-pharmacological interventions and tracing-testing strategy proved insufficient to reduce
SARS-CoV-2 spreading worldwide. Several vaccines with different mechanisms of action …
SARS-CoV-2 spreading worldwide. Several vaccines with different mechanisms of action …
Neoantigen-specific adoptive cell therapies for cancer: making T-cell products more personal
Mutation-derived neoantigens are taking central stage as a determinant in eliciting effective
antitumor immune responses following adoptive T-cell therapies. These mutations are …
antitumor immune responses following adoptive T-cell therapies. These mutations are …
[HTML][HTML] New generation vaccines for COVID-19 based on peptide, viral vector, artificial antigen presenting cell, DNA or mRNA
M Rezaei, M Nazari - Avicenna Journal of Medical Biotechnology, 2022 - ncbi.nlm.nih.gov
At present, effective vaccines have been developed as the most successful approaches for
preventing widespread infectious disease. The global efforts are focusing with the aim of …
preventing widespread infectious disease. The global efforts are focusing with the aim of …
RIG-1-like receptor activation synergizes with intratumoral alpha radiation to induce pancreatic tumor rejection, triple-negative breast metastases clearance, and …
V Domankevich, M Efrati, M Schmidt, E Glikson… - Frontiers in …, 2020 - frontiersin.org
Diffusing alpha-emitting radiation therapy (DaRT) employs intratumoral Ra-224-coated
seeds that efficiently destroy solid tumors by slowly releasing alpha-emitting atoms inside …
seeds that efficiently destroy solid tumors by slowly releasing alpha-emitting atoms inside …
Tsyn-Seq: a T-cell Synapse–Based Antigen Identification Platform
Y Jin, T Miyama, A Brown, T Hayase, X Song… - Cancer Immunology …, 2024 - AACR
Tools for genome-wide rapid identification of peptide–major histocompatibility complex
targets of T-cell receptors (TCR) are not yet universally available. We present a new antigen …
targets of T-cell receptors (TCR) are not yet universally available. We present a new antigen …
One-step shotgun approach for antigenic specific pMHCs capture stimulated CD8+ T cell activation and proliferation
L Liu, Y Li, Y Song, Z Sun, W Li, B Li, Y Wang… - Cellular …, 2023 - Elsevier
Antigenic peptides play a central role in immune surveillance in cancer, infectious disease,
autoimmunity, and allergy. The identification and isolation of antigenic peptides for T cell …
autoimmunity, and allergy. The identification and isolation of antigenic peptides for T cell …
Peptide–MHC complexes: dressing up to manipulate T cells against autoimmunity and cancer
Antigen-specificity of T cells provides important clues to the pathogenesis of T cell-mediated
autoimmune diseases and immune-evasion strategies of tumors. Identification of T cell …
autoimmune diseases and immune-evasion strategies of tumors. Identification of T cell …