Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …

Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Oligonucleotides (oligos) have been under clinical development for approximately the past
30 years, beginning with antisense oligonucleotides (ASOs) and apatmers and followed …

The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

The epithelial-mesenchymal transition (EMT) describes the global process by which
stationary epithelial cells undergo phenotypic changes, including the loss of cell-cell …

Growth factors have recently gained clinical importance for wound management. Application
of recombinant growth factors has been shown to mimic cell migration, proliferation, and …

The extracellular matrix (ECM) has pleiotropic effects, ranging from cell adhesion to cell
survival. In tissue engineering, the use of ECM and ECM-like scaffolds has separated the …

Wound healing is a complex and dynamic biological process that involves the coordinated
efforts of multiple cell types and is executed and regulated by numerous growth factors and …

Growth factors are important morphogenetic proteins that instruct cell behavior and guide
tissue repair and renewal. Although their therapeutic potential holds great promise in …