Codon usage bias: an endless tale
Since the genetic code is degenerate, several codons are translated to the same amino
acid. Although these triplets were historically considered to be “synonymous” and therefore …
acid. Although these triplets were historically considered to be “synonymous” and therefore …
The ecology and adaptive evolution of influenza A interspecies transmission
U Joseph, YCF Su, D Vijaykrishna… - Influenza and other …, 2017 - Wiley Online Library
Since 2013, there have been several alarming influenza‐related events; the spread of highly
pathogenic avian influenza H5 viruses into North America, the detection of H10N8 and …
pathogenic avian influenza H5 viruses into North America, the detection of H10N8 and …
Plasma cell-free RNA characteristics in COVID-19 patients
Y Wang, J Li, L Zhang, HX Sun, Z Zhang, J Xu… - Genome …, 2022 - genome.cshlp.org
The pathogenesis of COVID-19 is still elusive, which impedes disease progression
prediction, differential diagnosis, and targeted therapy. Plasma cell-free RNAs (cfRNAs) …
prediction, differential diagnosis, and targeted therapy. Plasma cell-free RNAs (cfRNAs) …
Deep mutational scanning reveals the functional constraints and evolutionary potential of the influenza A virus PB1 protein
Y Li, S Arcos, KR Sabsay, AJW Te Velthuis… - Journal of …, 2023 - Am Soc Microbiol
The influenza virus polymerase is central to influenza virus evolution. Adaptive mutations
within the polymerase are often a prerequisite for efficient spread of novel animal-derived …
within the polymerase are often a prerequisite for efficient spread of novel animal-derived …
Revelation of influencing factors in overall codon usage bias of equine influenza viruses
Equine influenza viruses (EIVs) of H3N8 subtype are culprits of severe acute respiratory
infections in horses, and are still responsible for significant outbreaks worldwide …
infections in horses, and are still responsible for significant outbreaks worldwide …
Novel approaches for the development of live attenuated influenza vaccines
P Blanco-Lobo, A Nogales, L Rodríguez… - Viruses, 2019 - mdpi.com
Influenza virus still represents a considerable threat to global public health, despite the
advances in the development and wide use of influenza vaccines. Vaccination with …
advances in the development and wide use of influenza vaccines. Vaccination with …
Insights into the genetic and host adaptability of emerging porcine circovirus 3
G Li, H Wang, S Wang, G Xing, C Zhang, W Zhang… - Virulence, 2018 - Taylor & Francis
ABSTRACT Porcine circovirus 3 (PCV3) was found to be associated with reproductive
disease in pigs, and since its first identification in the United States, it subsequently spread …
disease in pigs, and since its first identification in the United States, it subsequently spread …
Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution
Background Equine influenza is a major health problem of equines worldwide. The
polymerase genes of influenza virus have key roles in virus replication, transcription …
polymerase genes of influenza virus have key roles in virus replication, transcription …
Contribution of RNA-RNA interactions mediated by the genome packaging signals for the selective genome packaging of influenza A virus
S Miyamoto, Y Muramoto, K Shindo… - Journal of …, 2022 - Am Soc Microbiol
The influenza A virus genome is composed of eight single-stranded negative-sense viral
RNA segments (vRNAs). The eight vRNAs are selectively packaged into each progeny …
RNA segments (vRNAs). The eight vRNAs are selectively packaged into each progeny …
A synthetic biology approach for vaccine candidate design against delta strain of SARS-CoV-2 revealed disruption of favored codon pair as a better strategy over …
The SARS-CoV-2 delta variant (B. 1.617. 2) appeared for the first time in December 2020
and later spread worldwide. Currently available vaccines are not so efficacious in curbing …
and later spread worldwide. Currently available vaccines are not so efficacious in curbing …