Pain is a frequent and poorly treated symptom of Parkinson's disease, mainly due to scarce
knowledge of its basic mechanisms. In Parkinson's disease, deep brain stimulation of the …

While hyperalgesia (increased pain sensitivity) has been suggested to contribute to the
increased prevalence of clinical pain in Parkinson's disease (PD), experimental research is …

Pain is a common non-motor symptom of Parkinson's disease (PD), with current limited
knowledge of its pathophysiology. Here, we show that peripheral inoculation of mouse alpha …

Introduction Pain is a common and disabling non-motor symptom of Idiopathic Parkinson's
disease (PD) but its underlying pathophysiological mechanisms are not well understood …

Pain, one of the most frequent nonmotor symptoms of Parkinson disease (PD), is recognized
as an important component of the illness that adversely affects patient quality of life. The …

Chronic post-surgical pain (CPSP) is a debilitating condition affecting 10–50% of surgical
patients. The current treatment strategy for CPSP is not optimal, and the identification of …

Patients with Parkinson disease (PD) experience hyperalgesia on evoked pain sensitivity
testing, although the relationship of this with persistent pain in PD is less certain. Studies …

Objective: The purpose of this study was to investigate the acute effects of manual lymphatic
drainage (MLD) on pain threshold and pain tolerance of different body parts. Methods and …

People with Parkinson's disease (PD) may live for multiple decades after diagnosis.
Ensuring that effective healthcare provision is received across the range of symptoms …

Objective: To determine the presence of widespread pressure hyperalgesia in multiple
sclerosis (MS) patients with and without pain and its association with pain and fatigue …