The role of L-arginine metabolism in neurocritical care patients

MMD Mader, P Czorlich - Neural regeneration research, 2022 - journals.lww.com
Nitric oxide is an important mediator of vascular autoregulation and is involved in
pathophysiological changes after acute neurological disorders. Nitric oxide is generated by …

Integrating LC-MS and HS-GC-MS for the metabolite characterization of the Chinese medicinal plant Platostoma palustre under different processing methods

D Tang, C Quan, S Huang, F Wei - Frontiers in Nutrition, 2023 - frontiersin.org
Platostoma palustre (or Mesona chinensis Benth) is an important medicinal and edible plant
in China and Southeast Asian countries. To study the effects of different processing methods …

Effects of various therapeutic agents on vasospasm and functional outcome after aneurysmal subarachnoid hemorrhage–results of a network meta-analysis

S Mishra, K Garg, VB Gaonkar, PM Singh, M Singh… - World neurosurgery, 2021 - Elsevier
Background Vasospasm and delayed ischemic neurologic deficits are the leading causes of
morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH). Several …

Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage

MM Mader, R Böger, D Appel… - Journal of Cerebral …, 2021 - journals.sagepub.com
Alterations in the concentration of nitric oxide (NO) and L-arginine metabolites have been
associated with the pathophysiology of different vascular diseases. Here, we describe …

Arginase-1 released into CSF after aneurysmal subarachnoid hemorrhage decreases arginine/ornithine ratio: a novel prognostic biomarker

J Zimmermann, J Weller, S Grub, S Kebir… - Translational Stroke …, 2022 - Springer
We hypothesized that the enzyme arginase-1 is released into the cerebrospinal fluid (CSF)
during red blood cell lysis and contributes to dysregulated metabolism of the nitric oxide …

Chiral 5-fluorouracil-arginine cocrystals screened by wet powder grinding method: Leading to synergistic anti-tumor and alleviate cardiotoxicity

H Hao, T Ren, C Quan, J Wang - Powder Technology, 2024 - Elsevier
Arginine (ARG) is a precursor for producing NO, which can relax vascular smooth muscle.
We herein report cocrystals screened by powder grinding using chiral ARG to improve the …

[HTML][HTML] Analysis on efficacy of compound dextran combined with atorvastatin calcium in patients with CVS caused by SAH based on TCD blood flow indexes

Y Zhang, F Ma, N Gan, F Su, Z Song - Pakistan Journal of Medical …, 2022 - ncbi.nlm.nih.gov
Objectives: To analyze the effects of compound dextran combined with atorvastatin calcium
on blood flow indexes, peroxidase 2 (Prx2) and endothelin-1 (ET-1) in patients with cerebral …

L-精氨酸代谢在神经重症监护患者中的作用

MMD Mader, P Czorlich - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Nitric oxide is an important mediator of vascular autoregulation and is involved in
pathophysiological changes after acute neurological disorders. Nitric oxide is generated by …

[PDF][PDF] 精氨酸及其代谢产物对缺血性脑卒中的作用

丁涵青, 张颖, 韦璐瑶, 李紫… - Progress in Modern …, 2021 - biomed.cnjournals.com
缺血性脑卒中是成年人群致残, 致死的重要原因之一, 有效治疗手段和药物的匮乏是脑卒中致残
的主要原因. 精氨酸既是一种营养物质, 又具有多种独特的生理与药理作用, 在早产儿和严重应激 …

Effectiveness of the arginine-carnitine drug usage in patients with burn wounds| Український Медичний Часопис

OM Lynnyk, HP Kozynets, OO Diadyk… - Effectiveness of the …, 2023 - umj.com.ua
Aim: to study the effect of the combined arginine-carnitine drug in patients with burn wounds.
Materials and methods. 41 patients (18 in main group and 23 in comparison group) were …