The relation between thyroid function and depression has long been recognized. Patients
with thyroid disorders are more prone to develop depressive symptoms and conversely …

There has been an established relationship between hypothyroidism and depression.
Studies have demonstrated that somatostatin and serotonin influence the hypothalamus …

Thyroid hormones play a critical role in the metabolic activity of the adult brain, and
neuropsychiatric manifestations of thyroid disease have long been recognised. However, it …

Purpose The close association among thyroid metabolism, mood disorders and behavior
has long been known. The old and modern uses of thyroid hormones to modulate the …

Despite the remarkable increase in medications validated as effective in bipolar disorder,
treatment is still plagued by inadequate response in acute manic or depressive episodes or …

Background: A relationship between hypothyroidism and depression has been assumed for
many years; however, the true nature of this association has been difficult to define with …

Accumulating evidence suggests that hypothalamo‐pituitary‐thyroid (HPT) axis dysfunction
is relevant to the pathophysiology and clinical course of bipolar affective disorder …

Background Resistant bipolar disorder is a major mental health problem related to
significant disability and overall cost. The aim of the current study was to perform a …

Objectives Thyroid hormones play a critical role in the functioning of the adult brain, and
thyroid diseases impair both mood and cognition. This paper reviews gender differences in …

For more than 125 years 1 it has been recognized that thyroid disease may give rise to
psychiatric disorders that can be corrected by reestablishment of normal thyroid function …