RNA helicases are highly conserved proteins that use nucleoside triphosphates to bind or
remodel RNA, RNA–protein complexes or both. RNA helicases are classified into the DEAD …

Micro-RNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) that act as post-
transcriptional regulators of gene expression. Since their discovery in 1993, they have been …

MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. In animals, pri-miRNAs are cleaved by Drosha to …

MicroRNA (miRNA) and RNA interference (RNAi) pathways rely on small RNAs produced by
Dicer endonucleases. Mammalian Dicer primarily supports the essential gene-regulating …

MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …

Small RNA molecules regulate eukaryotic gene expression during development and in
response to stresses including viral infection. Specialized ribonucleases and RNA-binding …

In eukaryotic RNA silencing, RNase-III classes of enzymes in the Dicer family process
double-stranded RNA of cellular or exogenous origin into small-RNA (sRNA) molecules …

Mosquitoes live under the endless threat of infections from different kinds of pathogens such
as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical …

Dicer is a multidomain enzyme that generates small RNAs for gene silencing in eukaryotes.
Current understanding of Dicer structure is restricted to simple forms of the enzyme, whereas …

Summary Drosophila Dicer-1 produces microRNAs (miRNAs) from pre-miRNA, whereas
Dicer-2 generates small interfering RNAs (siRNAs) from long dsRNA. Alternative splicing of …