[HTML][HTML] Combatting resistance: understanding multi-drug resistant pathogens in intensive care units
J Teng, S Imani, A Zhou, Y Zhao, L Du, S Deng… - Biomedicine & …, 2023 - Elsevier
The escalating misuse and excessive utilization of antibiotics have led to the widespread
dissemination of drug-resistant bacteria, posing a significant global healthcare crisis. Of …
dissemination of drug-resistant bacteria, posing a significant global healthcare crisis. Of …
A comprehensive review on genomics, systems biology and structural biology approaches for combating antimicrobial resistance in ESKAPE pathogens …
In recent decades, antimicrobial resistance has been augmented as a global concern to
public health owing to the global spread of multidrug-resistant strains from different ESKAPE …
public health owing to the global spread of multidrug-resistant strains from different ESKAPE …
Multi-epitope vaccine for monkeypox using pan-genome and reverse vaccinology approaches
Outbreaks of monkeypox virus infections have imposed major health concerns worldwide,
with high morbidity threats to children and immunocompromised adults. Although …
with high morbidity threats to children and immunocompromised adults. Although …
Genomic analysis of the international high-risk clonal lineage Klebsiella pneumoniae sequence type 395
ER Shaidullina, M Schwabe, T Rohde… - Genome Medicine, 2023 - Springer
Background Klebsiella pneumoniae, which is frequently associated with hospital-and
community-acquired infections, contains multidrug-resistant (MDR), hypervirulent (hv), non …
community-acquired infections, contains multidrug-resistant (MDR), hypervirulent (hv), non …
Hybrid Plasmids Encoding Antimicrobial Resistance and Virulence Traits Among Hypervirulent Klebsiella pneumoniae ST2096 in India
Background Hypervirulent variants of Klebsiella pneumoniae (HvKp) were typically
associated with a broadly antimicrobial susceptible clone of sequence type (ST) 23 at the …
associated with a broadly antimicrobial susceptible clone of sequence type (ST) 23 at the …
Emergence of Meropenem Resistance Among Cefotaxime Non-susceptible Streptococcus pneumoniae: Evidence and Challenges
The principal causative agent of acute bacterial meningitis (ABM) in children and the elderly
is Streptococcus pneumoniae, with a widespread increase in penicillin resistance …
is Streptococcus pneumoniae, with a widespread increase in penicillin resistance …
Detection and characterization of putative hypervirulent Klebsiella pneumoniae isolates in microbiological diagnostics
B Neumann, C Stürhof, A Rath, B Kieninger, E Eger… - Scientific reports, 2023 - nature.com
Hypervirulent Klebsiella pneumoniae strains (hvKp) can cause invasive community-
acquired infections in healthy patients of all ages. In this study, the prevalence of putative …
acquired infections in healthy patients of all ages. In this study, the prevalence of putative …
[HTML][HTML] Network metrics, structural dynamics and density functional theory calculations identified a novel Ursodeoxycholic Acid derivative against therapeutic target …
Parkinson's disease (PD) has been designated as one of the priority neurodegenerative
disorders worldwide. Although diagnostic biomarkers have been identified, early onset …
disorders worldwide. Although diagnostic biomarkers have been identified, early onset …
Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and molecular …
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
Genomic Analysis of Multidrug-Resistant Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae Strain Lacking the Hypermucoviscous Regulators (rmpA/rmpA2 …
Hypervirulent K. pneumoniae (hvKP) strains possess distinct characteristics such as
hypermucoviscosity, unique serotypes, and virulence factors associated with high …
hypermucoviscosity, unique serotypes, and virulence factors associated with high …