[HTML][HTML] Organelle-specific regulation of ferroptosis

X Chen, R Kang, G Kroemer, D Tang - Cell Death & Differentiation, 2021 - nature.com
Ferroptosis, a cell death modality characterized by iron-dependent lipid peroxidation, is
involved in the development of multiple pathological conditions, including ischemic tissue …

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling

SC Koeberle, AP Kipp, H Stuppner… - Medicinal Research …, 2023 - Wiley Online Library
Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid
peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight …

Iron-containing protein-mimic supramolecular iron delivery systems for ferroptosis tumor therapy

S Liu, M Zhang, H Jin, Z Wang, Y Liu… - Journal of the …, 2022 - ACS Publications
Ferroptosis provides an innovative theoretical basis and method for tumor therapy but is
limited by the low efficiency of conventional iron delivery systems. Herein, an efficient …

Stem cell therapy in liver regeneration: Focus on mesenchymal stem cells and induced pluripotent stem cells

L Zhang, YY Fei, HT Han, J Xu, L Cheng, X Li - Pharmacology & …, 2022 - Elsevier
The liver has the ability to repair itself after injury; however, a variety of pathological changes
in the liver can affect its ability to regenerate, and this could lead to liver failure …

Ultrasmall Self-Cascade AuNP@FeS Nanozyme for H2S-Amplified Ferroptosis Therapy

J Zhan, J Liu, J Yang, L Huang, Y Lu, X Lu… - … applied materials & …, 2023 - ACS Publications
Recently, nanozymes with peroxidase (POD)-like activity have shown great promise for
ferroptosis-based tumor therapy, which are capable of transforming hydrogen peroxide …

Human liver cancer organoids: Biological applications, current challenges, and prospects in hepatoma therapy

L Chen, X Wei, D Gu, Y Xu, H Zhou - Cancer Letters, 2023 - Elsevier
Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …

Ferroptosis: an iron-dependent cell death form linking metabolism, diseases, immune cell and targeted therapy

S Li, Y Huang - Clinical and Translational Oncology, 2022 - Springer
Compared with the traditional forms of cell death—apoptosis, necrosis and autophagy,
ferroptosis is a novel form of iron-dependent programmed cell death forms which is different …

Fluorescent probes for lighting up ferroptotic cell death: A review

X Yang, S Zhang, M Lai, X Ji, Y Ye, J Tang, X Liu… - Talanta, 2023 - Elsevier
Ferroptosis is a newly discovered form of regulated cellular demise, characterized by the
accumulation of intracellular oxidative stress that is dependent on iron. Ferroptosis plays a …

Development of a high-throughput micropatterned agarose scaffold for consistent and reproducible hPSC-derived liver organoids

S Jiang, F Xu, M Jin, Z Wang, X Xu, Y Zhou… - …, 2022 - iopscience.iop.org
Liver organoids represent emerging human-relevant in vitro liver models that have a wide
range of biomedical applications in basic medical studies and preclinical drug discovery …

[HTML][HTML] Mitochondria-mediated ferroptosis in diseases therapy: from molecular mechanisms to implications

F Feng, S He, X Li, J He, L Luo - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Ferroptosis, a type of cell death involving iron and lipid peroxidation, has been found to be
closely associated with the development of many diseases. Mitochondria are vital …