The molecular hallmarks of the serrated pathway in colorectal cancer
Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different
subtypes that differ in their clinical and prognostic features. In the past decade, in addition to …
subtypes that differ in their clinical and prognostic features. In the past decade, in addition to …
Colorectal cancer: Genetic alterations, novel biomarkers, current therapeutic strategies and clinical trials
Colorectal cancer (CRC) is the third most commonly detected cancer with a serious global
health issue. The rates for incidence and mortality for CRC are alarming, especially since …
health issue. The rates for incidence and mortality for CRC are alarming, especially since …
Colorectal adenomas—genetics and searching for new molecular screening biomarkers
A Siskova, K Cervena, J Kral, T Hucl, P Vodicka… - International Journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new
cases per year worldwide. CRC outcome is closely related to the respective stage of CRC …
cases per year worldwide. CRC outcome is closely related to the respective stage of CRC …
Molecular features of the serrated pathway to colorectal cancer: current knowledge and future directions
C Satorres, M García-Campos… - Gut and …, 2020 - pmc.ncbi.nlm.nih.gov
Serrated lesions are the precursor lesions of a new model of colorectal carcinogenesis.
From a molecular standpoint, the serrated pathway is thought to be responsible for up to …
From a molecular standpoint, the serrated pathway is thought to be responsible for up to …
[HTML][HTML] What could microRNA expression tell us more about colorectal serrated pathway carcinogenesis?
M Peruhova, M Peshevska-Sekulovska… - World Journal of …, 2020 - ncbi.nlm.nih.gov
In the last two decades, the vision of a unique carcinogenesis model for colorectal
carcinoma (CRC) has completely changed. In addition to the adenoma to carcinoma …
carcinoma (CRC) has completely changed. In addition to the adenoma to carcinoma …
[HTML][HTML] Advances in microRNAs as Emerging Biomarkers for Colorectal Cancer Early Detection and Diagnosis
Colorectal cancer (CRC) remains the second most common cause of cancer-related
mortality worldwide, necessitating advancements in early detection and innovative treatment …
mortality worldwide, necessitating advancements in early detection and innovative treatment …
Approaches for sRNA analysis of human RNA-seq data: comparison, benchmarking
V Bezuglov, A Stupnikov, I Skakov… - International Journal of …, 2023 - mdpi.com
Expression analysis of small noncoding RNA (sRNA), including microRNA, piwi-interacting
RNA, small rRNA-derived RNA, and tRNA-derived small RNA, is a novel and quickly …
RNA, small rRNA-derived RNA, and tRNA-derived small RNA, is a novel and quickly …
Serrated lesions of the colon and rectum: Emergent epidemiological data and molecular pathways
Abstract In 2010, serrated polyps (SP) of the colon have been included in the WHO
classification of digestive tumors. Since then a large corpus of evidence focusing on these …
classification of digestive tumors. Since then a large corpus of evidence focusing on these …
A study of microRNAs as new prognostic biomarkers in anal cancer patients
O Dahl, MP Myklebust - Acta Oncologica, 2024 - pmc.ncbi.nlm.nih.gov
Background MicroRNA (MiR) influences the growth of cancer by regulation of mRNA for 50–
60% of all genes. We present as per our knowledge the first global analysis of microRNA …
60% of all genes. We present as per our knowledge the first global analysis of microRNA …
[HTML][HTML] Molecular characterization of sessile serrated adenoma/polyps from a large African American cohort
Colorectal cancer is the second leading cause of cancer-related deaths in the United States
and rates are highest among African Americans (AAs)(1). Sessile serrated adenoma/polyps …
and rates are highest among African Americans (AAs)(1). Sessile serrated adenoma/polyps …