Type 1 diabetes genome‐wide association studies: not to be lost in translation
F Pociot - Clinical & translational immunology, 2017 - Wiley Online Library
Genetic studies have identified> 60 loci associated with the risk of developing type 1
diabetes (T1D). The vast majority of these are identified by genome‐wide association …
diabetes (T1D). The vast majority of these are identified by genome‐wide association …
[HTML][HTML] Pathway analysis of complex diseases for GWAS, extending to consider rare variants, multi-omics and interactions
Background Genome-wide association studies (GWAS) is a major method for studying the
genetics of complex diseases. Finding all sequence variants to explain fully the aetiology of …
genetics of complex diseases. Finding all sequence variants to explain fully the aetiology of …
metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis
Motivation: A dominant approach to genetic association studies is to perform univariate tests
between genotype-phenotype pairs. However, analyzing related traits together increases …
between genotype-phenotype pairs. However, analyzing related traits together increases …
X chromosome contribution to the genetic architecture of primary biliary cholangitis
Background & Aims Genome-wide association studies in primary biliary cholangitis (PBC)
have failed to find X chromosome (chrX) variants associated with the disease. Here, we …
have failed to find X chromosome (chrX) variants associated with the disease. Here, we …
Genome-wide interaction and pathway-based identification of key regulators in multiple myeloma
S Chattopadhyay, H Thomsen, P Yadav… - Communications …, 2019 - nature.com
Inherited genetic susceptibility to multiple myeloma has been investigated in a number of
studies. Although 23 individual risk loci have been identified, much of the genetic heritability …
studies. Although 23 individual risk loci have been identified, much of the genetic heritability …
The left-liberal skew of Western media
EOW Kirkegaard, J Pallesen… - Journal of …, 2021 - journals.bilpubgroup.com
We gathered survey data on journalists' political views in 17 Western countries. We then
matched these data to outcomes from national elections, and constructed metrics of …
matched these data to outcomes from national elections, and constructed metrics of …
metaCCA: Summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis
A dominant approach to genetic association studies is to perform univariate tests between
genotype-phenotype pairs. However, analysing related traits together increases statistical …
genotype-phenotype pairs. However, analysing related traits together increases statistical …
Inherited genetic susceptibility to multiple myeloma and related diseases
S Chattopadhyay - 2019 - archiv.ub.uni-heidelberg.de
Monoclonal gammopathy of undetermined significance is the most common plasma cell
dyscrasia present in as high as 3.2% of general population below 50 years of age and up to …
dyscrasia present in as high as 3.2% of general population below 50 years of age and up to …