Individuals diagnosed with schizophrenia or bipolar disorder have a life expectancy 15–20
years shorter than that in the general population. The rate of unnatural deaths, such as …

Background Several studies and meta-analyses have shown that mortality in people with
schizophrenia is higher than that in the general population but have used relative measures …

Psychiatric patients have a greater risk of premature mortality, predominantly due to
cardiovascular diseases (CVDs). Convincing evidence shows that psychiatric conditions are …

Cognitive impairment is a core symptom domain of schizophrenia. The effect of
antipsychotics, the cornerstone of treatment in schizophrenia, on this domain is not fully …

People with psychotic disorders show abnormalities in several organ systems in addition to
the central nervous system (CNS); and this contributes to excess mortality. However, it is …

Schizophrenia (SCZ) and major depressive disorder (MDD) in treatment‐naive patients are
associated with increased risk for type 2 diabetes (T2D) and metabolic syndrome (MetS) …

Impairment of insulin action and metabolic dysregulation have traditionally been associated
with schizophrenia, although the molecular basis of such association remains still elusive …

Background: Schizophrenia is a complex illness in which genetic, environmental, and
epigenetic components have been implicated. However, recently, psychiatric disorders …

Metabolic disturbances and obesity are major cardiovascular risk factors in patients with
schizophrenia, resulting in a higher mortality rate and shorter life expectancy compared with …

The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …