[HTML][HTML] Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection

JA Nick, RM Dedrick, AL Gray, EK Vladar, BE Smith… - Cell, 2022 - cell.com
Two mycobacteriophages were administered intravenously to a male with treatment-
refractory Mycobacterium abscessus pulmonary infection and severe cystic fibrosis lung …

Toward better cures for Mycobacterium abscessus lung disease

V Dartois, T Dick - Clinical Microbiology Reviews, 2024 - journals.asm.org
The opportunistic pathogen Mycobacterium abscessus (Mab) causes fatal lung infections
that bear similarities—and notable differences—with tuberculosis (TB) pulmonary disease …

[HTML][HTML] Mycobacterial Biofilm: Mechanisms, Clinical Problems, and Treatments

X Liu, J Hu, W Wang, H Yang, E Tao, Y Ma… - International Journal of …, 2024 - mdpi.com
Tuberculosis (TB) remains a threat to human health worldwide. Mycobacterium tuberculosis
(Mtb) and other nontuberculous mycobacteria (NTM) can form biofilms, and in vitro and …

Dynamic mucus penetrating microspheres for efficient pulmonary delivery and enhanced efficacy of host defence peptide (HDP) in experimental tuberculosis

A Sharma, K Vaghasiya, P Gupta, AK Singh… - Journal of controlled …, 2020 - Elsevier
Pulmonary drug delivery system is increasingly gaining popularity for several lung diseases
including tuberculosis (TB) due to its ability to attain high drug concentrations at the site of …

An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus

K Zhang, J Limwongyut, AS Moreland… - Science Translational …, 2024 - science.org
Infections caused by nontuberculous mycobacteria have increased more than 50% in the
past two decades and more than doubled in the elderly population. Mycobacterium …

Knowledge and perception on antimicrobial resistance and antibiotics prescribing attitude among physicians and nurses in Lambaréné region, Gabon: a call for …

BR Adegbite, JR Edoa, F Schaumburg, AS Alabi… - … Resistance & Infection …, 2022 - Springer
Background Africa is challenged by the emergence of antimicrobial resistance (AMR). In
order to improve patient management and to optimise approaches to curb the spread of …

A leucyl-tRNA synthetase inhibitor with broad-spectrum antimycobacterial activity

US Ganapathy, R González del Rio… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Global infections by nontuberculous mycobacteria (NTM) are steadily rising. New drugs are
needed to treat NTM infections, but the NTM drug pipeline remains poorly populated and …

Alternative and Experimental Therapies of Mycobacterium abscessus Infections

M Meir, D Barkan - International journal of molecular sciences, 2020 - mdpi.com
Mycobacterium abscessus is a non-tuberculous mycobacterium notoriously known for
causing severe, chronic infections. Treatment of these infections is challenging due to either …

A rabbit model to study antibiotic penetration at the site of infection for nontuberculous mycobacterial lung disease: macrolide case study

F Kaya, JP Ernest, K LoMauro… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a potentially fatal infectious
disease requiring long treatment duration with multiple antibiotics and against which there is …

Eradication of nontuberculous mycobacteria in people with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor: a multicenter cohort study

V Wiesel, M Aviram, M Mei-Zahav, M Dotan… - Journal of Cystic …, 2024 - Elsevier
Background The prevalence of nontuberculous mycobacteria (NTM) infections is rising in
people with cystic fibrosis (pwCF). NTM infection, especially infection with Mycobacterium …