Chronic inflammatory lesions of the placenta are characterized by the infiltration of the organ
by lymphocytes, plasma cells, and/or macrophages and may result from infections (viral …

Organ transplantation appears today to be the best alternative to replace the loss of vital
organs induced by various diseases. Transplants can, however, also be rejected by the …

Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10
and CXCR3 in urine. Background We explored the hypothesis that measurements of mRNA …

The early identification of renal transplant recipients at enhanced risk of developing acute
and subclinical rejection would allow individualized adjustment of immunosuppression …

Interferon (IFN) γ-induced protein 10kDa (IP-10) or CXC motif chemokine 10 (CXCL10) is a
small cytokine belonging to the CXC chemokine family. This family of signaling molecules is …

Cells derived from the amniotic membranes of human term placenta have drawn much
interest for their characteristics of multipotency and low immunogenicity, supporting a variety …

Problem To determine whether amniotic fluid (AF) CXCL 10 concentration is associated with
histologic chronic chorioamnionitis in patients with preterm labor (PTL) and preterm prelabor …

A series of quinazolinone-derived inhibitors of the CXCR3 receptor have been synthesized
and their affinity for the receptor evaluated. Compounds were evaluated in a 125I-IP10 …

Identification of biomarkers that assess posttransplant risk is needed to improve long-term
outcomes following heart transplantation. The Clinical Trials in Organ Transplantation …

Regulatory T cells (Tregs) migrate into peripheral sites of inflammation such as allografts
undergoing rejection, where they serve to suppress the immune response. In this study, we …