The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors

P Møller, LE Knudsen, S Loft, H Wallin - Cancer epidemiology biomarkers & …, 2000 - AACR
Within the last decade, the comet assay has been used with increasing popularity to
investigate the level of DNA damage in terms of strand breaks and alkaline labile sites in …

The use of the alkaline comet assay with lymphocytes in human biomonitoring studies

F Faust, F Kassie, S Knasmüller, RH Boedecker… - … Research/Reviews in …, 2004 - Elsevier
We reviewed the data of 45 alkaline comet assay studies with lymphocytes published during
the last three years with the objective of monitoring human exposure to genotoxic agents as …

Cancer chemotherapy

DL Gustafson, RL Page - Withrow and MacEwen's small animal …, 2013 - books.google.com
The use of chemical elixirs for the treatment of cancer can be traced through the medicinal
customs and practices of a number of cultures. 1 The modern use of pharmacologic agents …

Evaluation of antineoplastic drug exposure of health care workers at three university-based US cancer centers

TH Connor, DG DeBord, JR Pretty… - … of occupational and …, 2010 - journals.lww.com
Objective: This study evaluated health care worker exposure to antineoplastic drugs.
Methods: A cross-sectional study examined environmental samples from pharmacy and …

Environmental and occupational biomonitoring using the Comet assay

M Valverde, E Rojas - Mutation Research/Reviews in Mutation Research, 2009 - Elsevier
Biomonitoring of human populations exposed to potential mutagens or carcinogens can
provide an early detection system for the initiation of cell disregulation in the development of …

Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention …

BJ Majer, B Laky, S Knasmüller, F Kassie - Mutation Research/Reviews in …, 2001 - Elsevier
This review summarises the current database on the micronucleus (MN) assay with
exfoliated cells (MEC assay) and evaluates the predictive value of this model for the …

Biological and environmental monitoring of hospital personnel exposed to antineoplastic agents: a review of analytical methods

R Turci, C Sottani, G Spagnoli, C Minoia - Journal of Chromatography B, 2003 - Elsevier
In order to assess occupational exposure of hospital personnel involved in the preparation
and administration of antineoplastic drugs, biological and environmental monitoring are …

Assessment of reference values for DNA damage detected by the comet assay in human blood cell DNA

P Møller - Mutation research/reviews in mutation research, 2006 - Elsevier
Genotoxicity measured by the comet assay is expressed by different researchers using
parameters that are not easy to conceptualize, except for percent tail DNA (% T) or visual …

Cancer incidence and adverse pregnancy outcome in registered nurses potentially exposed to antineoplastic drugs

PA Ratner, JJ Spinelli, K Beking, M Lorenzi, Y Chow… - BMC nursing, 2010 - Springer
Background To determine the relationships of potential occupational exposure to
antineoplastic drugs with cancer incidence and adverse pregnancy outcomes in a historical …

Evaluation of DNA damage in workers occupationally exposed to pesticides using single-cell gel electrophoresis (SCGE) assay: pesticide genotoxicity revealed by …

V Garaj-Vrhovac, D Zeljezic - Mutation Research/Genetic Toxicology and …, 2000 - Elsevier
The comet assay, also called the single-cell gel electrophoresis (SCGE) assay, is a rapid
and sensitive method for the detection of DNA damage (strand breaks and alkali-labile sites) …