Suppressing or enhancing macrophage engulfment through the use of CD47 and related peptides

AAR Jalil, MP Tobin, DE Discher - Bioconjugate chemistry, 2022 - ACS Publications
Foreign particles and microbes are rapidly cleared by macrophages in vivo, although many
key aspects of uptake mechanisms remain unclear.“Self” cells express CD47 which …

Enhancing immunogenicity in metastatic melanoma: adjuvant therapies to promote the anti-tumor immune response

S Pelka, C Guha - Biomedicines, 2023 - mdpi.com
Advanced melanoma is an aggressive form of skin cancer characterized by low survival
rates. Less than 50% of advanced melanoma patients respond to current therapies, and of …

Modulating macrophage-mediated programmed cell removal: An attractive strategy for cancer therapy

Z Li, B Han, M Qi, Y Li, Y Duan, Y Yao - Biochimica et Biophysica Acta (BBA …, 2024 - Elsevier
Macrophage-mediated programmed cell removal (PrCR) is crucial for the identification and
elimination of needless cells that maintain tissue homeostasis. The efficacy of PrCR …