Age-related macular degeneration (AMD) is a chronic and progressive degenerative
disease of the retina, which culminates in blindness and affects mainly the elderly …

Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

Retinal cell survival requires an equilibrium between oxygen, reactive oxygen species, and
antioxidant molecules that counteract oxidative stress damage. Oxidative stress alters cell …

The blood retinal barrier (BRB) is a fundamental eye component, whose function is to select
the flow of molecules from the blood to the retina and vice-versa, and its integrity allows the …

Introduction With the recent FDA approvals of pegcetacoplan (SYFOVRE, Apellis
Pharmaceuticals) and avacincaptad pegol (IZERVAY, Astellas Pharmaceuticals) …

Age-related macular degeneration (AMD) is the main cause of vision loss among the elderly
in the Western world. While AMD is a multifactorial disease, the complement system was …

Although the exact pathogenetic mechanisms leading to age-related macular degeneration
(AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an …

Age‐related macular degeneration (AMD) is a major cause of vision impairment in the
Western World, and with the aging world population, its incidence is increasing. As of today …

Age‐related macular degeneration (AMD) is a multifactorial disease, which can culminate in
irreversible vision loss and blindness in elderly. Nowadays, there is a big gap between dry …

Age-related macular degeneration (AMD) is among the leading causes of irreversible
blindness worldwide. In addition to environmental risk factors, such as tobacco use and diet …