Transbronchial cryobiopsies for the diagnosis of diffuse parenchymal lung diseases: expert statement from the cryobiopsy working group on safety and utility and a …

J Hetzel, F Maldonado, C Ravaglia, AU Wells… - Respiration, 2018 - karger.com
Transbronchial cryobiopsies (TBCB) have recently been introduced as a promising and
safer alternative to surgical lung biopsy in the diagnostic approach to diffuse parenchymal …

Interstitial lung disease

KM Antoniou, GA Margaritopoulos… - European …, 2014 - Eur Respiratory Soc
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …

Acute exacerbation of idiopathic pulmonary fibrosis: shifting the paradigm

CJ Ryerson, V Cottin, KK Brown… - European Respiratory …, 2015 - Eur Respiratory Soc
The goal of this review is to summarise the clinical features, management, and prognosis of
acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). AE-IPF has previously been …

Unmet needs in the treatment of idiopathic pulmonary fibrosis―insights from patient chart review in five European countries

TM Maher, M Molina-Molina, AM Russell… - BMC pulmonary …, 2017 - Springer
Background Two antifibrotic drugs, pirfenidone and nintedanib, are approved by the
European Medicines Agency and the US Food and Drug Administration for the treatment of …

Pirfenidone in idiopathic pulmonary fibrosis: real-life experience from a German tertiary referral center for interstitial lung diseases

U Oltmanns, N Kahn, K Palmowski, A Träger, H Wenz… - Respiration, 2014 - karger.com
Background: Pirfenidone is a novel antifibrotic drug for the treatment of mild-to-moderate
idiopathic pulmonary fibrosis (IPF). However, adverse events may offset treatment benefits …

Comorbidities in interstitial lung diseases

GA Margaritopoulos, KM Antoniou… - European Respiratory …, 2017 - Eur Respiratory Soc
Fibrosing lung disorders include a large number of diseases with diverse behaviour.
Patients can die because of the progression of their illness, remain stable or even improve …

Survival in idiopathic pulmonary fibrosis acute exacerbations: the non-steroid approach

SA Papiris, K Kagouridis, L Kolilekas… - BMC pulmonary …, 2015 - Springer
Background Idiopathic pulmonary fibrosis acute exacerbation (IPF-AE) constitutes IPF's most
devastating event, representing the unexpected superimposition of diffuse alveolar damage …

Safety and efficacy of S-1 in combination with carboplatin in non-small cell lung cancer patients with interstitial lung disease: a pilot study

A Sekine, H Satoh, T Baba, S Ikeda, R Okuda… - Cancer chemotherapy …, 2016 - Springer
Purpose There is no established standard regimen for non-small cell lung cancer (NSCLC)
patients with interstitial lung disease (ILD). For them, we performed a pilot study to evaluate …

Protective effect of bevacizumab on chemotherapy-related acute exacerbation of interstitial lung disease in patients with advanced non-squamous non-small cell lung …

S Hamada, H Ichiyasu, T Ikeda, M Inaba… - BMC pulmonary …, 2019 - Springer
Background Acute exacerbation of interstitial lung disease (AE-ILD) is the most serious
complication in lung cancer patients with pre-existing ILD receiving chemotherapy. The role …

iTRAQ-based proteomics reveals novel biomarkers for idiopathic pulmonary fibrosis

R Niu, Y Liu, Y Zhang, Y Zhang, H Wang, Y Wang… - PloS one, 2017 - journals.plos.org
Idiopathic pulmonary fibrosis (IPF) is a gradual lung disease with a survival of less than 5
years post-diagnosis for most patients. Poor molecular description of IPF has led to …