Serum response factor: toggling between disparate programs of gene expression

JM Miano - Journal of molecular and cellular cardiology, 2003 - Elsevier
Serum response factor (SRF) is a widely expressed transcription factor involved in
orchestrating disparate programs of gene expression linked to muscle differentiation and …

Muscarinic receptor signaling in the pathophysiology of asthma and COPD

R Gosens, J Zaagsma, H Meurs, AJ Halayko - Respiratory research, 2006 - Springer
Anticholinergics are widely used for the treatment of COPD, and to a lesser extent for
asthma. Primarily used as bronchodilators, they reverse the action of vagally derived …

Effect of zinc-doped hydroxyapatite/graphene nanocomposite on the physicochemical properties and osteogenesis differentiation of 3D-printed polycaprolactone …

H Maleki-Ghaleh, MH Siadati, A Fallah… - Chemical Engineering …, 2021 - Elsevier
Processing and composition can significantly affect the mechanobiology, biodegradability,
and cellular behavior of polymer-based bone scaffolds to replace damaged bone tissue. In …

Signaling and regulation of G protein-coupled receptors in airway smooth muscle

CK Billington, RB Penn - Respiratory research, 2003 - Springer
Signaling through G protein-coupled receptors (GPCRs) mediates numerous airway smooth
muscle (ASM) functions including contraction, growth, and" synthetic" functions that …

Myocardin in biology and disease

JM Miano - Journal of biomedical research, 2014 - pmc.ncbi.nlm.nih.gov
Myocardin (MYOCD) is a potent transcriptional coactivator that functions primarily in cardiac
muscle and smooth muscle through direct contacts with serum response factor (SRF) over …

'Practice without theory': a neuroanthropological perspective on embodied learning

G Downey - Journal of the Royal Anthropological Institute, 2010 - Wiley Online Library
This paper, drawing on research on skill acquisition and sports training, asks two questions.
First, how does the mimetic channel function and thus limit what can be acquired by bodily …

Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling

R Gosens, IST Bos, J Zaagsma… - American journal of …, 2005 - atsjournals.org
Rationale: Recent findings have demonstrated that muscarinic M3 receptor stimulation
enhances airway smooth muscle proliferation to peptide growth factors in vitro. Because …

Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis

N Regamey, M Ochs, TN Hilliard… - American journal of …, 2008 - atsjournals.org
Rationale: Structural alterations to airway smooth muscle (ASM) are a feature of asthma and
cystic fibrosis (CF) in adults. Objectives: We investigated whether increase in ASM mass is …

Regulation of vascular smooth muscle cells by micropatterning

RG Thakar, F Ho, NF Huang, D Liepmann… - … and biophysical research …, 2003 - Elsevier
Vascular smooth muscle cells (SMCs) undergo morphological and phenotypic changes
when cultured in vitro. To investigate whether SMC morphology regulates SMC functions …

SM22α modulates vascular smooth muscle cell phenotype during atherogenesis

S Feil, F Hofmann, R Feil - Circulation research, 2004 - Am Heart Assoc
The function of cytoskeletal proteins in the modulation of vascular smooth muscle cell (SMC)
phenotype during vascular disease is poorly understood. In this report, we used a …