Coeliac disease is a common enteropathy that occurs in genetically susceptible individuals
in response to the ingestion of gluten proteins present in wheat, rye and barley. Currently …

The autoimmune thyroid diseases (AITD) comprise a cadre of complex diseases whose
underlying pathoetiology stems from a genetic–environmental interaction, between …

Ferritin is a ubiquitous and specialised protein involved in the intracellular storage of iron; it
is also present in serum and other biological fluids, although its secretion processes are still …

Celiac Disease (CeD) is defined as a chronic small intestinal immune-mediated enteropathy
that is precipitated by exposure to dietary gluten in genetically predisposed individuals. CeD …

Chronic inflammation is a common theme in a variety of disease pathways, including
autoimmune diseases. The pathways of chronic inflammation are well illustrated by …

Autoimmune disease (AD) affects approximately 3% of the population. This is an enormous
number, but ironically the study of autoimmunity has not taken on the significance of many …

Aims Abdominal aortic aneurysm (AAA) is characterized by extensive aortic wall matrix
degradation that contributes to the remodelling and eventual rupture of the arterial wall …

Wegener's Granulomatosis (WG) is closely associated with antineutrophil cytoplasmic
autoantibodies (ANCA), particularly those directed to proteinase 3 (PR3). ANCA directed to …

Glucocorticoids (GCs) are widely used to treat several diseases because of their powerful
anti-inflammatory and immunomodulatory effects on immune cells and non-lymphoid …

Progressive multifocal leukoencephalopathy (PML) is a rare and devastating neurological
disease with areas of demyelination in the central nervous system classically associated …